Study of Mental Fatigue in Polio Survivors

NCT00487487 | Unknown

• 1 other identifier: USUHS-G192EI
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Post-Poliomyelitis Syndrome (PPS) is the term describing the new problems affecting polio survivors many years after recovery from paralytic polio. Among the symptoms, fatigue is one of the most frequent and debilitating. In addition to physical incapacitation, the fatigue of PPS also affects mental function. The term "brain fatigue" is usually used by patients to express problems on the areas of attention, concentration, memory and clear thinking. Unfortunately, little is known about cognitive fatigue of PPS patients. This study is meant to examine if mental impairment is present in PPS patients and, if so, how it interferes on the self-function of patients. Patients will undergo an interview, clinical and neurological evaluation, and a battery of screening laboratory tests to make sure they are eligible for the study. Patients who qualify will undergo neuropsychometric tests in order to assay performance in the main areas of cognitive functioning. Through this organized approach we expect to be able to determine if mental fatigue is a significant problem affecting polio survivors, what areas are most affected, and how it may interfere with daily living.

Conditions

Post-Poliomyelitis Syndrome

Keywords

Candidates for this study are survivors of paralytic poliomyelitis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years of age or older
• Be a survivor of poliomyelitis
• Willing to attend two clinic visits for completion of screening procedures and required tests

You may not qualify if:

• Suffer from medical conditions that can interfere with cognitive function, including stroke, traumatic brain injury, dementia (progressive memory loss), severe depression, psychosis or other psychiatric disorders, etc.

Sponsors & Collaborators

• Uniformed Services University of the Health Sciences: lead

Study Sites (1)

Postpolio Syndrome Outpatient Research Office

Rockville, Maryland, 20852, United States

RECRUITING

MeSH Terms

Conditions

Postpoliomyelitis Syndrome

Condition Hierarchy (Ancestors)

Poliomyelitis; Myelitis; Central Nervous System Infections; Infections; Enterovirus Infections; Picornaviridae Infections; RNA Virus Infections; Virus Diseases; Muscular Disorders, Atrophic; Muscular Diseases; Musculoskeletal Diseases; Central Nervous System Diseases; Nervous System Diseases; Spinal Cord Diseases; Neurodegenerative Diseases; Neuroinflammatory Diseases; Neuromuscular Diseases

Central Study Contacts

Sandra Maxwell, RN

CONTACT

301-9840400; smaxwell@usuhs.edu

Study Design

• Study Type: observational
• Time Perspective: OTHER
• Sponsor Type: FED

Study Record Dates

• First Submitted: June 14, 2007
• First Posted: June 18, 2007
• Last Updated: June 18, 2007

Record last verified: 2007-03

Locations

US (1)