Cardiac Arrest Recovery EEG Study

NCT00483873 | Unknown DMC

• 1 other identifier: R44HL070129
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 4

Brief Summary

The purpose of the study is to collect EEG's as close to the cardiac arrest as possible using a standard hospital EEG machine and an investigational EEG device to help determine the neurological status of the cardiac arrest patient and to help decide on possible treatment and chance of recovery. The investigational EEG machine will be simple to operate as well as easy to interpret for the clinician and the nurses. It is not to replace the electrophysiologist interpretation but to determine ealy on if further evaluation and treatment can help the patient.

Conditions

Cardiac Arrest; Arrhythmia

Keywords

Cardiac Arrest, Neurological Recovery, EEG, Quantitative EEG

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients admitted to the hospital after out-of-hospital Cardiac arrest or for an ICD placement

You may qualify if:

• Cardiac Arrest:
• Patients 18 years and older:
• with cardiac arrest in the hospital and successfully resuscitated, or
• with cardiac arrest out of the hospital and successfully resuscitated
• ICD patients:
• Patients 18 years and older:
• Who are undergoing elective procedure in the electrophysiology laboratory for placement of a cardiac defibrillator and who will most likely undergo induction of ventricular arrhythmia as part of the procedure

You may not qualify if:

• Cardiac Arrest:
• Cardiac arrest and a known pre-existing cerebral pathology such as brain tumor, cerebral hemorrhage, encephalitis or immediately post-op neurosurgery.
• CNS infection
• Skull defects and scalp diseases that are not amenable to standard EEG testing
• ICD patients:
• Known pre-existing cerebral pathology such as brain tumor, cerebral hemorrhage, encephalitis or immediately post-op neurosurgery.
• CNS infection
• Skull defects and scalp diseases that are not amenable to standard EEG testing

Sponsors & Collaborators

• Infinite Biomedical Technologies: lead
• National Heart, Lung, and Blood Institute (NHLBI): collaborator
• Johns Hopkins Bloomberg School of Public Health: collaborator
• Johns Hopkins University: collaborator
• Medical College of Wisconsin: collaborator
• Virginia Commonwealth University: collaborator

Study Sites (4)

Johns Hopkins Hospital

Baltimore, Maryland, 21187, United States

RECRUITING

Johns Hopkins Bayview Medical Center

Baltimore, Maryland, 21224, United States

RECRUITING

Virginia Commonwealth University

Richmond, Virginia, 23298, United States

NOT YET RECRUITING

Medical College of Wisconsin at Froedtert Memorial Luthern Hospital Clinics - Neurology

Milwaukee, Wisconsin, 53226, United States

RECRUITING

MeSH Terms

Conditions

Heart Arrest; Arrhythmias, Cardiac

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Neil S Rothman, PhD

  Infinite Biomedical Technologies - Study Sponsor

  PRINCIPAL INVESTIGATOR

• Romergryko Geocadin, MD

  Johns Hopkins University

  PRINCIPAL INVESTIGATOR

• Michel Torbey, MD, MPH

  Medical College of Wisconsin

  PRINCIPAL INVESTIGATOR

• Mary Ann Peberdy, MD

  Virginia Commonwealth University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Romergryko Geocadin, MD

CONTACT

410-614-6145; rgeocadi@jhmi.edu

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY

Study Record Dates

• First Submitted: June 6, 2007
• First Posted: June 7, 2007
• Study Start: August 1, 2007
• Study Completion: December 1, 2009
• Last Updated: January 29, 2009

Record last verified: 2009-01

Locations

US (4)