Health-Related Quality of Life in Patients With Dupuytren's Disease

NCT00468949 | Completed

• 1 other identifier: 06-2713
• Study Type: observational
• Target: 51
• Locations: 1 country
• Sites: 1

Brief Summary

Main Research Questions: We want to measure the change in quality of life in Dupuytren's disease patients who do and do not undergo surgery. Also, we want to test the validity of health related quality of life measurements in patients with Dupuytren's disease. Why is this research important? Some patients with Dupuytren's contracture require excision surgery or palmar fasciectomy. Other patient's with Dupuytren's contracture do not require surgery; however, these patients may need surgery in the future. No studies have reported the health-related quality of life of patients with Dupuytren's disease whether related to surgical intervention or not. What is being studied? We are studying the difference and change in health-related quality of life in patients suffering from Dupuytren's disease who require excision surgery and do not require surgery.

Conditions

Dupuytren's Contracture

Keywords

Health-Related Quality of Life; Dupuytren's Disease; Health Utilities Index; Short Form-36;; Michigan Hand Outcomes Questionnaire

Study Arms (2)

1

Patients undergoing excision surgery for their dupuytren's contracture

2

Patients not undergoing surgery for their excision surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with dupuytren's contracture

You may qualify if:

• patients who have the diagnosis of Dupuytren's disease
• able to comprehend English to complete the self-reported questionnaires
• willing to provide informed consent.

You may not qualify if:

• patients who have had previous Dupuytren's contracture surgery on the same hand
• patients who have carpal tunnel syndrome, rheumatoid arthritis, connective tissue disorder, tenosynovitis, or another condition that could affect quality of life
• patients who are under the age of 18 years.

Sponsors & Collaborators

• Hamilton Health Sciences Corporation: lead
• McMaster University: collaborator

Study Sites (1)

St. Joseph's Healthcare

Hamilton, Ontario, L8N 4A6, Canada

Location

Related Publications (1)

• Thoma A, Kaur MN, Ignacy TA, Levis C, Martin S, Duku E, Haines T. Health-related quality of life in patients undergoing palmar fasciectomy for Dupuytren's disease. Plast Reconstr Surg. 2014 Jun;133(6):1411-1419. doi: 10.1097/PRS.0000000000000177.

  PMID: 24569424 DERIVED

MeSH Terms

Conditions

Dupuytren Contracture

Condition Hierarchy (Ancestors)

Fibroma; Neoplasms, Fibrous Tissue; Neoplasms, Connective Tissue; Neoplasms, Connective and Soft Tissue; Neoplasms by Histologic Type; Neoplasms; Contracture; Muscular Diseases; Musculoskeletal Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases

Study Officials

• Achilleas Thoma, MD MSC

  St. Josephs Hamilton Health Care / McMaster University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: May 2, 2007
• First Posted: May 3, 2007
• Study Start: May 1, 2007
• Primary Completion: July 1, 2011
• Study Completion: July 1, 2011
• Last Updated: July 28, 2011

Record last verified: 2011-07

Locations

CA (1)