NCT00465140

Brief Summary

Creatine (CR) supplementation is commonly used by athletes. However, its effects on renal function remain controversial. The aim of this study was to evaluate the effects of creatine supplementation on renal function and oxidative stress in healthy sedentary males (18-35 years old) submitted to exercise training. Our hipothesis is that creatine supplementation does not affect renal function in this population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2004

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2004

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2007

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

April 23, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 24, 2007

Completed
Last Updated

April 24, 2007

Status Verified

April 1, 2007

First QC Date

April 23, 2007

Last Update Submit

April 23, 2007

Conditions

Renal Insufficiency

Interventions

creatine supplementationDRUG
aerobic exercise trainingBEHAVIORAL

Eligibility Criteria

Age18 Years - 35 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Sedentary healthy males,
  • Euthrofic,
  • Age beteween 18-35 y

You may not qualify if:

  • Food supplement users,
  • Pre-existing renal dysfunction,
  • Pre-existing cardioavascular disease,
  • Subjetcs physically active or athletes,
  • Obesity,
  • Drugs users

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Sao Paulo

São Paulo, São Paulo, 55 11, Brazil

Location

MeSH Terms

Conditions

Renal Insufficiency

Interventions

Creatine

Condition Hierarchy (Ancestors)

Kidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

GuanidinesAmidinesOrganic ChemicalsAmino AcidsAmino Acids, Peptides, and Proteins

Study Officials

  • Bruno Gualano, ms

    University of Sao Paulo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 23, 2007

First Posted

April 24, 2007

Study Start

January 1, 2004

Study Completion

January 1, 2007

Last Updated

April 24, 2007

Record last verified: 2007-04

Locations

BR(1)