Loading search results
CORONARY
CABG Off or On Pump Revascularization Study (CORONARY)
Sponsor study identifier
interventional
4,752
13 countries
52
Study Start
October 2007
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
March 2012
Actual (reported)Study Completion
September 2016
Actual (reported)I. Main Research Question:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
September 2016
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 18, 2007
Actual (reported)April 20, 2007
Actual (reported)October 2007
Date type not reportedThis date has not been verified as actual or estimated.
March 2012
Actual (reported)September 2016
Actual (reported)First Co-Primary Outcome
The occurrence of the composite of total mortality, stroke, nonfatal MI, or new renal failure at 30 days post CABG surgery
30 days post CABG surgery
Second co-primary outcome
The occurrence of the composite of total mortality, stroke, nonfatal MI, new renal failure, or repeat coronary revascularization (i.e. coronary artery bypass surgery or percutaneous coronary intervention) over 5 years after randomization.
5 years after CABG
The assessment of total costs and resources consumption at 30 days after CABG surgery
30 days after CABG surgery
The assessment of total costs and resources consumption at 5 years after CABG surgery
5 years after CABG surgery
Coronary Artery Bypass Graft (CABG) using median sternotomy, CPB, cardioplegia and complete cross-clamp and no associated or concomitant surgical procedures
Coronary Artery Bypass Graft (CABG) with no associated or concomitant surgical procedures, using median sternotomy and without CPB and cardioplegia
Fundacion Medica de rio negro y neuquen
Rio Negro, Argentina
Beneficencia Portuguesa de Sao Paulo
São Paulo, CEP, 01323.001, Brazil
Instituto Dante Pazzanese de Cardiologia
São Paulo, CEP, 04012-909, Brazil
Hospital Sao Francisco Complexo Hospitalar Santa Casa
Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
Irmande Santa Casa De Misericordia De Curtiba
Curitiba Parana, 80010030, Brazil
Braile Clinica de Servicos de Assistencia Medico
São José do Rio Preto, 15091-450, Brazil
Irmandade da Santa Casa de Misericordia de Sao Paulo
Dimagli A, Gaudino M, An KR, Olaria RP, Soletti GJ, Cancelli G, Harik L, Noiseux N, Stevens LM, Lamy A; CORONARY investigators. Five-Year Hospital Readmission After Coronary Artery Bypass Surgery and the Association With Off-Pump Surgery and Sex. J Am Heart Assoc. 2023 Apr 18;12(8):e028063. doi: 10.1161/JAHA.122.028063. Epub 2023 Apr 7.
Hebert M, Lamy A, Noiseux N, Stevens LM; CORONARY Investigators. Impact of early quantitative morbidity on 1-year outcomes in coronary artery bypass graft surgery. Interact Cardiovasc Thorac Surg. 2022 Mar 31;34(4):523-531. doi: 10.1093/icvts/ivab316.
Lamy Andre, MD, MSc
McMaster University
Salim Yusuf, MD, DPhil
Population Health Research Institute
David Taggart, MD
University of Oxford
4,752 participants (actual enrollment reported by the registry).
First Submitted
April 18, 2007
First Posted
April 20, 2007
Study Start
October 2007
Date type not reportedThis date has not been verified as actual or estimated.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
São Paulo, 01221-020, Brazil
Federal University of Sao Paulo School of Medicine
São Paulo, 04024-002, Brazil
Associação do Sanátorio Sírio
São Paulo, 04038-030, Brazil
Instituto do Coracao do Hospital das Clinicas da
São Paulo, 05403-00, Brazil
Hospital Mario Covas
São Paulo, 09190-615, Brazil
Santa Casa de Misericordia de Marilia
São Paulo, 17515-000, Brazil
Foothills Medical Centre
Calgary, Alberta, T2N 2T9, Canada
Hamilton General Hospital
Hamilton, Ontario, L8L 2X2, Canada
London Health Sciences Centre
London, Ontario, N6A 5A5, Canada
Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
Montreal Heart Institute
Montreal, Quebec, H1T 1C8, Canada
Hotel-Dieu du CHUM
Montreal, Quebec, H2W 1T8, Canada
Hospital Regional Temuco
Temuco, Araucania, Chile
Instituto Nacional del Torax
Santiago, Chile
ChaoYang Hospital
Beijing, China
FuWai Hospital
Beijing, China
Nanjing First Hospital
Nanjing, China
Fundacion Cardioinfantil
Bogotá, Colombia
Fundacion Valle Del Lili
Cali, Colombia
Charles University Hospital
Hradec Králové, 50005, Czechia
Kardiochirurgicke centrum
Ostrava-Poruba, 708 52, Czechia
University Hospital Pilsen
Pilsen, 304 60, Czechia
Fakultni nemocnice Kralovske Vinohrady (FNKV)
Prague, 100 34, Czechia
University Hospital Motol
Prague, 150 00, Czechia
Nemocnice Podlesi
Třinec, 739 61, Czechia
Service de chirurgie thoracique et cardio-vasculaire
Besançon, 25030, France
Nizam's Institute of Medical Sciences
Hyderabad, Andhra Pradesh, 500 082, India
SAL Hospital and Medical Institute
Ahmedabad, Gujarat, 380054, India
Amrita Institute of Medical Sciences and Research Center
Kochi, Kerala, 682 026, India
G.Kuppuswamy Naidu Memorial Hospital
Coimbatore, Tamil Nadu, 641 037, India
SAL Hospital
Ahmedabad, India
International Center of Cardiovascular and Thoracic Diseases
Chennai Tamil Nadu, 600101, India
Sanjay Gandhi PGIMS
Lucknow, 226 014, India
All India Institute of Medical Sciences
New Delhi, 110016, India
Escorts Heart Institute and Research Centre
Noida, 201307, India
Ospedale S. Croce
Cuneo, 12100, Italy
Ospedale Niguarda - Ca Granda
Milan, 20162, Italy
Jagiellonian University
Krakow, 31-202, Poland
Alp Aslan
Ankara, Turkey (Türkiye)
Erol Senor
Ankara, Turkey (Türkiye)
Ruchan Akar
Ankara, Turkey (Türkiye)
Sertap Aykut Aka
Ankara, Turkey (Türkiye)
Volkan Sinci
Ankara, Turkey (Türkiye)
Basildon and Thurrock University Hospital NHS FT
Basildon, Essex, SS16 5NL, United Kingdom
Royal Infirmary of Edinburgh
Edinburgh, EU, 16 4SU, United Kingdom
The John Radcliffe Hospital
Oxford, OX3 9DU, United Kingdom
Conen D, Wang MK, Devereaux PJ, Whitlock R, McIntyre WF, Healey JS, Yuan F, Yusuf S, Lamy A. New-Onset Perioperative Atrial Fibrillation After Coronary Artery Bypass Grafting and Long-Term Risk of Adverse Events: An Analysis From the CORONARY Trial. J Am Heart Assoc. 2021 Jun 15;10(12):e020426. doi: 10.1161/JAHA.120.020426. Epub 2021 May 29.
Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Straka Z, Piegas LS, Avezum A, Akar AR, Lanas Zanetti F, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Gao P, Pettit S, Yusuf S; CORONARY Investigators. Five-Year Outcomes after Off-Pump or On-Pump Coronary-Artery Bypass Grafting. N Engl J Med. 2016 Dec 15;375(24):2359-2368. doi: 10.1056/NEJMoa1601564. Epub 2016 Oct 23.
Lamy A, Tong W, Devereaux PJ, Gao P, Gafni A, Singh K, Taggart D, Straka Z, Akar AR, Piegas L, Ou Y, Yusuf S. The cost implications of off-pump versus on-pump coronary artery bypass graft surgery at one year. Ann Thorac Surg. 2014 Nov;98(5):1620-5. doi: 10.1016/j.athoracsur.2014.06.046. Epub 2014 Sep 24.
Garg AX, Devereaux PJ, Yusuf S, Cuerden MS, Parikh CR, Coca SG, Walsh M, Novick R, Cook RJ, Jain AR, Pan X, Noiseux N, Vik K, Stolf NA, Ritchie A, Favaloro RR, Parvathaneni S, Whitlock RP, Ou Y, Lawrence M, Lamy A; CORONARY Investigators. Kidney function after off-pump or on-pump coronary artery bypass graft surgery: a randomized clinical trial. JAMA. 2014 Jun 4;311(21):2191-8. doi: 10.1001/jama.2014.4952.
Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Paolasso E, Straka Z, Piegas LS, Akar AR, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Vaijyanath P, Reddy SK, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Pogue J, Chrolavicius S, Yusuf S; CORONARY Investigators. Effects of off-pump and on-pump coronary-artery bypass grafting at 1 year. N Engl J Med. 2013 Mar 28;368(13):1179-88. doi: 10.1056/NEJMoa1301228. Epub 2013 Mar 11.
Garg AX, Devereaux PJ, Yusuf S, Cuerden MS, Parikh CR, Coca SG, Walsh M, Cook RJ, Whitlock RP, Noiseux N, Novick RJ, Ou Y, Lamy A; CORONARY Investigators. Coronary Artery Bypass Grafting Surgery Off- or On-pump Revascularisation Study (CORONARY): kidney substudy analytic protocol of an international randomised controlled trial. BMJ Open. 2012 Apr 18;2(2):e001080. doi: 10.1136/bmjopen-2012-001080. Print 2012.
Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Paolasso E, Straka Z, Piegas LS, Akar AR, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Vaijyanath P, Reddy S, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Ng J, Chrolavicius S, Yusuf S; CORONARY Investigators. Off-pump or on-pump coronary-artery bypass grafting at 30 days. N Engl J Med. 2012 Apr 19;366(16):1489-97. doi: 10.1056/NEJMoa1200388. Epub 2012 Mar 26.
Lamy A, Devereaux PJ, Prabhakaran D, Hu S, Piegas LS, Straka Z, Paolasso E, Taggart D, Lanas F, Akar AR, Jain A, Noiseux N, Ou Y, Chrolavicius S, Ng J, Yusuf S. Rationale and design of the coronary artery bypass grafting surgery off or on pump revascularization study: a large international randomized trial in cardiac surgery. Am Heart J. 2012 Jan;163(1):1-6. doi: 10.1016/j.ahj.2011.10.007.
Primary Completion
March 2012
Actual (reported)Study Completion
September 2016
Actual (reported)Last Updated
September 16, 2016
Record last verified: 2016-09
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: