Sponsor study identifier
observational
0
1 country
1
Study Start
July 1988
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
Not reported
Date not reportedTransplant rejection following organ transplant occurs because the recipient's immune system attacks the transplanted organ. The recipients immune system recognizes the transplanted organ as foreign tissue and attempts to destroy it in the similar way that it attempts to destroy infectious agents such as bacteria and viruses. The human leukocyte antigen (HLA) system is a set of genes that is responsible for controlling an individuals' ability to tell the difference between an infectious agent and self tissue. Differences in HLA genes between donors and recipients play a major part in influencing the rejection or acceptance of foreign tissue (i.e. transplanted organs). Due to time limitations in heart transplantation, HLA matching is not considered. It is unclear how individual HLA differences affect the recovery and expected lifespan of pediatric heart transplant recipients. This study is designed to look at the donor-recipient matching and mismatching to determine if mismatching leads to more complications, shorter graft survival and, therefore, increased risk of death following pediatric heart transplantation.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
Not reported
Date not reportedClick on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 1988
Date type not reportedThis date has not been verified as actual or estimated.
April 16, 2007
Actual (reported)April 17, 2007
Actual (reported)* heart transplants at Childrens Healthcare of Atlanta, Egleston Hospital * transplants between July 1, 1988 through and including January 31, 2007 * complete HLA data * survived more than 30 days after transplant
Emory University
Atlanta, Georgia, 30322, United States
Robert Bray, PhD
Emory University
0 participants (actual enrollment reported by the registry).
First Submitted
April 16, 2007
First Posted
April 17, 2007
Study Start
July 1988
Date type not reportedThis date has not been verified as actual or estimated.
Respiratory Motion Analysis in Children With MRI
Contact the study team to confirm eligibility.
Last Updated
December 31, 2013
Record last verified: 2013-12
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Source: ClinicalTrials.gov.
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