NCT00367354

Terminated

Respiratory Motion Analysis in Children With MRI

Emory University Source

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Other study identifiers

Sponsor study identifier

IRB00041134

Study Type

observational

Actual enrollment (reported)

6

Locations

1 country

Sites

1

Timeline

Study Start

August 2006

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

June 2010

Actual (reported)

Study Completion

July 2011

Actual (reported)

Brief Summary

The purpose of this project is to analyze the respiratory motion process as relevant in cardiac MRI imaging and apply the results for development of improved imaging methods and software correction. To accomplish this, we will develop an imaging protocol for monitoring respiratory motion. The imaging protocol will be limited to less than five minutes of acquisition time so it may be performed as "piggyback" acquisition following clinically prescribed imaging studies on pediatric and adult cardiac MRI patients, but will also be applied to normal healthy volunteers. Hypothesis Characterization of respiratory motion will help improve image quality by allowing optimized scan acquisition and retrospective correction of acquired data.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: terminated
Actual enrollment (reported): 6 participants
Study completion date: July 2011
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

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Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
August 2006
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
August 18, 2006
Actual (reported)
First Posted
August 22, 2006
Actual (reported)
Primary Completion
June 2010
Actual (reported)
Study Completion
July 2011
Actual (reported)

Last Updated: December 9, 2014
Status Verified: December 2014
Last Update Submitted: December 8, 2014

Conditions

Congenital Disorders

Keywords

Imaging TechnologyCardiology

Outcome Measures

Primary Outcomes (1)

cardiac motion reduction in cardiac MRI images
throughout study

Eligibility Criteria

Sexall

Healthy VolunteersYes

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

35 healthy volunteers (21 years or older) and 25 cardiac MRI patients of different age groups.

You may qualify if:

We will recruit two groups of patients - 35 healthy volunteers (21 years or older) and 25 cardiac MRI patients of different age groups.

Sponsors & Collaborators

Emory University
Otherlead

Study Sites (1)

Emory University Hospital

Atlanta, Georgia, 30322, United States

MeSH Terms

Conditions

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

William Mahle
Emory University
PRINCIPAL INVESTIGATOR

Enrollment

6 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Principal Investigator

Study Record Dates

First Submitted

August 18, 2006

First Posted

August 22, 2006

Study Start

August 2006

Date type not reported

This date has not been verified as actual or estimated.

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We wish to recruit cardiac patients from Children's Healthcare of Atlanta into five (5) different categories defined by the overall characteristics of breathing motion. The categories are:

neonates/infants (shallow belly breathing)

young children (unable to do controlled breathing or breath-holding on command, up to approximately 7 years of age)

older children capable of controlled breathing/breath-holding on command (approximately 8-12 years of age)

teenagers/adolescents/young adults (ages 13 through 17)

adults (18 and older) These categories may be adjusted or modified during the project as deemed appropriate based on the analysis results.

We will recruit 10 - 35 healthy volunteer subjects for scans to define the MRI imaging protocol for respiratory motion monitoring. Healthy subjects are defined as those individuals who do not have a prior history of heart or lung disease nor are currently diagnosed with heart or lung disease. This information will be obtained verbally during the subject screening process.

You may not qualify if:

subjects with pacemakers, medical implants, aneurysm clips, or imbedded metal fragments will be excluded because of potential effects of the magnetic field
women who are pregnant or who may be pregnant will be excluded because of the potential of a high level of RF power deposition on the fetus
subjects who may experience claustrophobia will be excluded because of their inability to remain in the magnet for the time required to complete the exam

Contact the study team to confirm eligibility.

Primary Completion

June 2010

Actual (reported)

Study Completion

July 2011

Actual (reported)

Last Updated

December 9, 2014

Record last verified: 2014-12

Source record

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Source: ClinicalTrials.gov.

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Registry identifier: NCT00367354
Data provider: ClinicalTrials.gov
Source updated: 2014-12-09
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:27:29 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations