NCT00452205

Brief Summary

The purpose of this study is to clarify the relationship bone marrow-derived cells and the formation of the tumors, and the role of these cells in regeneration of epithelial cells in the gastrointestinal tract.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2007

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 26, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 27, 2007

Completed
5 days until next milestone

Study Start

First participant enrolled

April 1, 2007

Completed
9.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2017

Completed
Last Updated

August 4, 2009

Status Verified

August 1, 2009

First QC Date

March 26, 2007

Last Update Submit

August 3, 2009

Conditions

Gastrointestinal Neoplasms

Keywords

bone marrow-derived stem cellbone marrow transplantationgraft versus host diseasegastrointestinal cancerafter receiving bone marrow transplantation

Eligibility Criteria

Age20 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients received bone marrow transplantation in Tokyo Metropolitan Komagome Hospital

You may qualify if:

  • After allogeneic bone marrow transplantation

You may not qualify if:

  • Contraindication for gastrointestinal endoscopy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cancer and Infection Disease Center, Komagome

Tokyo, Bunkyo-ku, 113-8677, Japan

RECRUITING

Related Publications (1)

  • Houghton J, Stoicov C, Nomura S, Rogers AB, Carlson J, Li H, Cai X, Fox JG, Goldenring JR, Wang TC. Gastric cancer originating from bone marrow-derived cells. Science. 2004 Nov 26;306(5701):1568-71. doi: 10.1126/science.1099513.

    PMID: 15567866BACKGROUND

Biospecimen

Retention: SAMPLES WITH DNA

tissue

MeSH Terms

Conditions

Gastrointestinal NeoplasmsGraft vs Host Disease

Condition Hierarchy (Ancestors)

Digestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesImmune System Diseases

Study Officials

  • Naoto Egawa, MD

    STUDY DIRECTOR

Central Study Contacts

Naoto Egawa, MD

CONTACT

+81-3-3823-2101naoto@cick.jp

Hisashi Sakamaki, MD

CONTACT

+81-3-3823-2101sakamaki@cick.jp

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 26, 2007

First Posted

March 27, 2007

Study Start

April 1, 2007

Study Completion

March 1, 2017

Last Updated

August 4, 2009

Record last verified: 2009-08

Locations

JP(1)