NCT00447109

Brief Summary

The purpose of this study was to compare the incidence of ventilator-associated pneumonia between two groups of patients randomised to have closed system suction catheter changes every 24 hours and patients having closed system suction catheter changes every seven days or as required.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
344

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2003

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2003

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2004

Completed
2.9 years until next milestone

First Submitted

Initial submission to the registry

March 12, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 14, 2007

Completed
Last Updated

March 14, 2007

Status Verified

March 1, 2007

First QC Date

March 12, 2007

Last Update Submit

March 13, 2007

Conditions

Pneumonia, Ventilator AssociatedClosed System Suction Catheter

Outcome Measures

Primary Outcomes (1)

  • ventilator-associated pneumonia

Secondary Outcomes (6)

  • length of hospital

  • intensive care stay

  • duration of mechanical ventilation

  • hospital mortality

  • number of acquired organ system derangements

  • +1 more secondary outcomes

Interventions

Closed system suctionDEVICE

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged greater than 18 years
  • Mechanically ventilated for more than 24 hours

You may not qualify if:

  • Admitted from other hospital already mechanically ventilated
  • Massive haemoptysis
  • Previously received mechanical ventilation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Alfred Hospital

Melbourne, Victoria, 3181, Australia

Location

MeSH Terms

Conditions

Pneumonia, Ventilator-Associated

Condition Hierarchy (Ancestors)

Healthcare-Associated PneumoniaCross InfectionInfectionsPneumoniaRespiratory Tract InfectionsLung DiseasesRespiratory Tract DiseasesIatrogenic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Lauren J McTier

    Deakin University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

March 12, 2007

First Posted

March 14, 2007

Study Start

September 1, 2003

Study Completion

April 1, 2004

Last Updated

March 14, 2007

Record last verified: 2007-03

Locations

AU(1)