NCT00432718

Brief Summary

Compare the incidence of ventilator associated pneumonia with or without tracheal isotonic saline instillation before tracheal suctioning

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
260

participants targeted

Target at P75+ for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2001

Completed
5.5 years until next milestone

First Submitted

Initial submission to the registry

February 7, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 8, 2007

Completed
Last Updated

February 8, 2007

Status Verified

February 1, 2007

First QC Date

February 7, 2007

Last Update Submit

February 7, 2007

Conditions

Mechanical VentilationCritically Ill Patients

Keywords

PneumoniaVentilator Associated PneumoniaPrevention

Outcome Measures

Primary Outcomes (1)

  • incidence of ventilator associated pneumonia

Secondary Outcomes (2)

  • atelectasis

  • tube occlusion

Interventions

Saline Instillation before Tracheal SuctioningPROCEDURE

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Consecutive patients foreseen to receive mechanical ventilation for more than 72 hours

You may not qualify if:

  • Previous mechanical ventilation in the last month
  • Mechanical ventilation for more than 6 hours before arrival at ICU,
  • Contraindication to bronchoscopy and
  • Be expected to die or undergo withdrawal treatment within 48 hours-

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

ICU Hospital do Câncer

São Paulo, São Paulo, 01509-010, Brazil

Location

MeSH Terms

Conditions

PneumoniaPneumonia, Ventilator-Associated

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsLung DiseasesRespiratory Tract DiseasesHealthcare-Associated PneumoniaCross InfectionIatrogenic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Pedro Caruso, MD

    Intensive Care Unit - Hospital do Câncer and University of Sao Paulo Medical School

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
PREVENTION
Intervention Model
FACTORIAL
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 7, 2007

First Posted

February 8, 2007

Study Start

August 1, 2001

Last Updated

February 8, 2007

Record last verified: 2007-02

Locations

BR(1)