NCT00431587

Brief Summary

The metabolic risks associated with obesity are closely correlated with central (abdominal), rather than a peripheral (gluteofemoral) fat pattern It has been shown that weight loss after bariatric surgery is followed by metabolic improvements. The amount of fat lost from each site may be independently regulated. Very scant information is found in the literature regarding the relative changes in different fat body compartments, and their effect on the improvement of the metabolic profile. In this study we define the absolute and relative changes in the different adipose tissue compartment after weight loss surgery

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 5, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 6, 2007

Completed
4 months until next milestone

Study Start

First participant enrolled

June 1, 2007

Completed
Last Updated

April 17, 2008

Status Verified

January 1, 2007

First QC Date

February 5, 2007

Last Update Submit

April 16, 2008

Conditions

Morbid ObesityMetabolic SyndromeVisceral Obesity

Keywords

morbid obesitymetabolic syndromevisceral fatperipheral fat

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Morbid obesity,
  • Metabolic syndrome

You may not qualify if:

  • Previous abdominoplasty surgery,
  • Previous major abdominal surgey

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hadassah Medical Organization,

Jerusalem, Israel

RECRUITING

Related Publications (1)

  • Weiss R, Appelbaum L, Schweiger C, Matot I, Constantini N, Idan A, Shussman N, Sosna J, Keidar A. Short-term dynamics and metabolic impact of abdominal fat depots after bariatric surgery. Diabetes Care. 2009 Oct;32(10):1910-5. doi: 10.2337/dc09-0943. Epub 2009 Jul 8.

    PMID: 19587363DERIVED

MeSH Terms

Conditions

Obesity, MorbidMetabolic SyndromeObesity, Abdominal

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsInsulin ResistanceHyperinsulinismGlucose Metabolism DisordersMetabolic Diseases

Study Officials

  • Andrei Keidar, MD

    Hadassah Medical Organization

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Andrei Keidar, MD

CONTACT

00 972 2 6777384andreik@hadassah.org.il

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 5, 2007

First Posted

February 6, 2007

Study Start

June 1, 2007

Last Updated

April 17, 2008

Record last verified: 2007-01

Locations

IL(1)