NCT00419107

Brief Summary

Diabetes is more frequent in women with Turner syndrome. The purpose of this study is to see, in what ways the glucose metabolism is different in this study population. The hypothesis is that women with Turner Syndrome have an impaired insulin production (beta cell function).

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2004

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2004

Completed
2.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2007

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

January 5, 2007

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 8, 2007

Completed
Last Updated

November 8, 2011

Status Verified

November 1, 2011

First QC Date

January 5, 2007

Last Update Submit

November 7, 2011

Conditions

Turner Syndrome

Eligibility Criteria

Age20 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

13 women with TS and 12 control women

You may qualify if:

  • Turner syndrome

You may not qualify if:

  • Diagnosed diabetes
  • BMI\>30
  • Untreated cardiac or thyroid disease
  • Cancer illness

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical Department M (Endocrinology and Diabetes), Aarhus University Hospital

Aarhus, Aarhus C, 8000, Denmark

Location

Related Publications (1)

  • Hjerrild BE, Holst JJ, Juhl CB, Christiansen JS, Schmitz O, Gravholt CH. Delayed beta-cell response and glucose intolerance in young women with Turner syndrome. BMC Endocr Disord. 2011 Mar 15;11:6. doi: 10.1186/1472-6823-11-6.

    PMID: 21406078DERIVED

Biospecimen

Retention: SAMPLES WITH DNA

Blood samples.

MeSH Terms

Conditions

Turner Syndrome

Condition Hierarchy (Ancestors)

Gonadal DysgenesisDisorders of Sex DevelopmentUrogenital AbnormalitiesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesSex Chromosome Disorders of Sex DevelopmentMale Urogenital DiseasesHeart Defects, CongenitalCardiovascular AbnormalitiesCardiovascular DiseasesHeart DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesSex Chromosome DisordersChromosome DisordersGenetic Diseases, InbornGonadal DisordersEndocrine System Diseases

Study Officials

  • Jens Sandahl Christiansen, prof. dr.med

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 5, 2007

First Posted

January 8, 2007

Study Start

November 1, 2004

Study Completion

January 1, 2007

Last Updated

November 8, 2011

Record last verified: 2011-11

Locations

DK(1)