NCT00418652

Brief Summary

Trans Cranial Magnetic Stimulation (TMS) over dorsal visual system will disturb the ability to identify objects with decreased level of fragmentation

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2006

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

January 4, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 5, 2007

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2010

Completed
Last Updated

August 4, 2011

Status Verified

August 1, 2011

Enrollment Period

4.5 years

First QC Date

January 4, 2007

Last Update Submit

August 3, 2011

Conditions

Healthy

Keywords

Normal Controls

Outcome Measures

Primary Outcomes (1)

  • Results of the study assignments performed by the participants during the study.

    The subjects performed 2 tasks: The primary dependent measures consisted of the level of detail needed for correct object identification, response accuracy, and response time in milliseconds for correct responses. Illusory Contour Task: Subjects also performed a pulsed pedestal task, Participants were shown 55 drawings for 500 ms each. Some drawings contained partial contours which defined a geometric shape, while in others the contours did not define a shape. Participants were asked to indicate whether they recognized a geometric shape or not. Accuracy and response time were measured.

    The participants performed the tasks once during their study visit

Study Arms (3)

No TMS stimulation

NO INTERVENTION

The patients performed 2 tasks: a study and a control assignments with no TMS stimulation.

Device: No TMS intervention

TMS over the dorsal stream

EXPERIMENTAL

The patients performed 2 tasks: a study and a control assignments under TMS stimulation over the dorsal stream area (PO3 EEG site).

Device: TMS over the PO3 EEG site

TMS over the vertex

SHAM COMPARATOR

The patients performed 2 tasks: a study and a control assignments under TMS stimulation over the vertex area.

Device: TMS over the vertex

Interventions

No TMS interventionDEVICE

In the "no TMS" condition, no simulation was given and no coil placed near participants' heads.

No TMS stimulation
TMS over the PO3 EEG siteDEVICE

10Hz TMS over the dorsal stream (PO3 EEG site)

Also known as: MAGSTIM biphasic stimulator
TMS over the dorsal stream
TMS over the vertexDEVICE

10Hz TMS for over vertex.

Also known as: MAGSTIM biphasic stimulator
TMS over the vertex

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Normal controls

You may not qualify if:

  • neurological, ophthalmological or psychiatric problems
  • family history of schizophrenia
  • left handed

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Psychiatry Clinic - Sheba Medical Center

Tel Litwinsky, 52621, Israel

Location

Study Officials

  • Revital Amiaz, MD

    Sheba Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

January 4, 2007

First Posted

January 5, 2007

Study Start

January 1, 2006

Primary Completion

July 1, 2010

Last Updated

August 4, 2011

Record last verified: 2011-08

Locations

IL(1)