NCT00400712

Brief Summary

Once discharged from hospital many stroke survivors deteriorate medically, physically and in their mobility function and many report their level of function and quality of life to be poor 12 months after inpatient rehabilitation. There is an identified need for follow-up examinations of community dwelling stroke survivors to monitor changes in function and it has been suggested that maintenance therapy could curtail declines in function. The purpose of this trial is to determine whether brief periods of intense client-centered rehabilitation therapy (tune-ups) provided at 6 month intervals can alter the natural progression of impairment (physical capacity), function and community reintegration following stroke.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
103

participants targeted

Target at P75+ for not_applicable stroke

Timeline
Completed

Started Dec 2006

Longer than P75 for not_applicable stroke

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 16, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 17, 2006

Completed
14 days until next milestone

Study Start

First participant enrolled

December 1, 2006

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2012

Completed
4.3 years until next milestone

Results Posted

Study results publicly available

May 5, 2016

Completed
Last Updated

May 5, 2016

Status Verified

April 1, 2016

Enrollment Period

4.9 years

First QC Date

November 16, 2006

Results QC Date

November 6, 2015

Last Update Submit

April 3, 2016

Conditions

Keywords

mobilitystrengthbalancefunctionreintegrationcommunity

Outcome Measures

Primary Outcomes (3)

  • Subjective Index of Physical and Social Outcome (SIPSO)

    The SIPSO is a 10-item measure developed specifically for stroke that includes a Physical Integration Subscale relating to activities and daily living and a Social Integration subscale relating to social adaptation. Each item is assessed on an ordinal scale from 0 (cannot perform the task or activity/completely dissatisfied) to 4 (no difficultly/completely satisfied) such that the minimum score is 0 and the maximum for each subscale is 20 and the maximum total score is 40 (sum of subscales). The total score reflects reintegration.

    baseline and 1 year

  • Subjective Index of Social Integration (Subscale of SIPSO)

    see Subjective Index of Physical and Social Outcome (SIPSO) above

    baseline and one year

  • Subjective Index of Physical Integration (Subscale of SIPSO)

    see 'Subjective Index of Physical and Social Outcome (SIPSO) above

    baseline and one year

Secondary Outcomes (4)

  • Mobility Function

    baseline and 1 year

  • Physical Capacity

    baseline and 12 months

  • Health-related Quality of Life - Physical

    baseline and one year

  • Health-related Quality of Life - Mental

    baseline and one year

Study Arms (2)

Control

NO INTERVENTION

natural progression post-stroke

Intervention

EXPERIMENTAL

two weeks of goal directed intensive physical rehabilitation therapy at 6 months (and one year)

Behavioral: physical rehabilitation

Interventions

two weeks intensive physical rehabilitation

Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • first major unilateral hemispheric stroke,
  • english speaking,
  • adequate verbal communication,
  • discharged home or residential care

You may not qualify if:

  • serious comorbidities (eg. cancer, mobility limiting arthritis, leg amputation)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Queen's University School of Rehabilitation Therapy

Kingston, Ontario, K7L 3N6, Canada

Location

School of Physical Therapy, University of Western Ontario

London, Ontario, N6G 1H1, Canada

Location

Related Publications (2)

  • Brouwer B, Bryant D, Garland SJ. Effectiveness of Client-Centered "Tune-Ups" on Community Reintegration, Mobility, and Quality of Life After Stroke: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2018 Jul;99(7):1325-1332. doi: 10.1016/j.apmr.2017.12.034. Epub 2018 Apr 3.

  • Cohen JW, Ivanova TD, Brouwer B, Miller KJ, Bryant D, Garland SJ. Do Performance Measures of Strength, Balance, and Mobility Predict Quality of Life and Community Reintegration After Stroke? Arch Phys Med Rehabil. 2018 Apr;99(4):713-719. doi: 10.1016/j.apmr.2017.12.007. Epub 2018 Jan 6.

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Results Point of Contact

Title
Brenda Brouwer
Organization
Queen's University

Study Officials

  • Brenda J Brouwer, PhD

    Queen's University

    PRINCIPAL INVESTIGATOR
  • Jayne Garland, Ph.D

    Western University, Canada

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle investigator

Study Record Dates

First Submitted

November 16, 2006

First Posted

November 17, 2006

Study Start

December 1, 2006

Primary Completion

November 1, 2011

Study Completion

January 1, 2012

Last Updated

May 5, 2016

Results First Posted

May 5, 2016

Record last verified: 2016-04

Locations