NCT00395096|Completed
Environmental Exposures, Genetics, and Exhaled Nitric Oxide in Pediatric Asthma
Environmental Exposures, NOS Genes, and Exhaled Nitric Oxide in Pediatric Asthma
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Environmental Exposures, NOS Genes, and Exhaled Nitric Oxide in Pediatric Asthma
Sponsor study identifier
Secondary identifiers
observational
225
1 country
1
Study Start
July 2006
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
June 2008
Actual (reported)Study Completion
June 2008
Actual (reported)Asthma is one of the most common childhood diseases. It is chronic and often severely disabling. The amount of nitric oxide that is exhaled while breathing increases with airway inflammation, a symptom of asthma. This study will examine the results from a previous study, the Cincinnati Asthma Prevention (CAP) study, to evaluate the effects of environmental and genetic factors on exhaled nitric oxide (eNO) levels and to determine the relationship between eNO and asthma severity.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 2008
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 2006
Date type not reportedThis date has not been verified as actual or estimated.
October 31, 2006
Actual (reported)November 2, 2006
Actual (reported)June 2008
Actual (reported)June 2008
Actual (reported)Effects of environmental and genetic factors on exhaled nitric oxide (eNO) levels and the relationship between eNO and asthma severity
Measured through the use of data previously collected in the Cincinnati Asthma Prevention (CAP) study
Cincinnati area children with asthma
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229-3039, United States
Spanier AJ, Hornung R, Lierl M, Lanphear BP. Environmental exposures and exhaled nitric oxide in children with asthma. J Pediatr. 2006 Aug;149(2):220-6. doi: 10.1016/j.jpeds.2006.04.001.
Wilson SE, Kahn RS, Khoury J, Lanphear BP. Racial differences in exposure to environmental tobacco smoke among children. Environ Health Perspect. 2005 Mar;113(3):362-7. doi: 10.1289/ehp.7379.
Blood and urine
Adam J. Spanier, MD, MPH
Children's Hospital Medical Center, Cincinnati
225 participants (actual enrollment reported by the registry).
First Submitted
October 31, 2006
First Posted
November 2, 2006
Study Start
July 2006
Date type not reportedThis date has not been verified as actual or estimated.
Airflow Obstruction and Biomarkers of Airway Inflammation During and Following Acute Exacerbations of Childhood Asthma
Contact the study team to confirm eligibility.
Primary Completion
June 2008
Actual (reported)Study Completion
June 2008
Actual (reported)Last Updated
August 9, 2021
Record last verified: 2009-02
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Source: ClinicalTrials.gov.
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