NCT00394849

Brief Summary

The purpose of this study is to determine if closing the tonsil fossa after tonsillectomy leads to less pain and bleeding risk than leaving it open to heal by secondary intention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
763

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2000

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2000

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2004

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2004

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

October 30, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 1, 2006

Completed
Last Updated

November 7, 2017

Status Verified

November 1, 2017

Enrollment Period

3.7 years

First QC Date

October 30, 2006

Last Update Submit

November 3, 2017

Conditions

Keywords

TonsillectomySuturing of tonsillar pillarspainpostoperative hemorrhage, bleeding

Outcome Measures

Primary Outcomes (1)

  • which side was more painful on or about postoperative day 14

    determined which side was more painful on or about postoperative day 14 by asking patient and/or care giver

    14 days

Secondary Outcomes (4)

  • Additional information was obtained about details if postoperative bleeding occurred, including which side bled and details of the event

    40 days

  • any other adverse events (complications)

    40 days

  • which side was more painful on or about postoperative day 21

    21 days

  • overall assessment at the postoperative clinic visit (on or about day 28)

    28 days

Study Arms (2)

suture one tonsillar fossa

EXPERIMENTAL

Intervention: one tonsillar fossa was sutured. One side was not sutured. Pain was compared side to side.

Procedure: suture one tonsillar fossa

One side not sutured

NO INTERVENTION

Intervention: one tonsillar fossa was sutured. One side was not sutured. Pain was compared side to side.

Interventions

one tonsillar fossa was sutured. One side was not sutured. Pain was compared side to side.

suture one tonsillar fossa

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Any patient for whom tonsillectomy is recommended for recurrent pharyngitis, obstructive sleep disorder, snoring, halitosis, feeding difficulty associated with adenotonsillar hypertrophy, and who in the investigator's opinion, is capable of providing reliable responses to post-operative follow-up questions as defined in this protocol.

You may not qualify if:

  • Any patient for whom tonsillectomy is recommended for suspected malignancy or active peritonsillar abscess

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Riley Childrens' Hospital

Indianapolis, Indiana, 46202, United States

Location

Related Publications (1)

  • Matt BH, Krol BJ, Ding Y, Juliar BE. Effect of tonsillar fossa closure on postoperative pain and bleeding risk after tonsillectomy. Int J Pediatr Otorhinolaryngol. 2012 Dec;76(12):1799-805. doi: 10.1016/j.ijporl.2012.09.004. Epub 2012 Sep 25.

MeSH Terms

Conditions

HemorrhagePainPostoperative Hemorrhage

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and SymptomsNeurologic ManifestationsSigns and SymptomsPostoperative Complications

Study Officials

  • Bruce H. Matt, MD, MS

    Indiana University School of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
did not tell participant which side was sutured.
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: sutured one tonsillar fossa. pain was compared side to side. which side was sutured was randomized
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 30, 2006

First Posted

November 1, 2006

Study Start

July 1, 2000

Primary Completion

March 1, 2004

Study Completion

March 1, 2004

Last Updated

November 7, 2017

Record last verified: 2017-11

Data Sharing

IPD Sharing
Will not share

Locations