NCT00393926

Brief Summary

The purpose of the study is to examine how a novel robot technology designed for eventual use as a home therapy can improve arm function after stroke.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at P25-P50 for phase_1 stroke

Timeline
Completed

Started Jul 2006

Longer than P75 for phase_1 stroke

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2006

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

October 30, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 31, 2006

Completed
6.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2013

Completed
Last Updated

February 4, 2014

Status Verified

February 1, 2014

Enrollment Period

6.9 years

First QC Date

October 30, 2006

Last Update Submit

February 3, 2014

Conditions

Keywords

RoboticsRehabilitationUpper ExtremityCVA

Interventions

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subjects will be included in the study on the basis of the following criteria:
  • They must be at least six months post-stroke.
  • years of age or older with a clinical diagnosis of hemiparesis (as verified by medical record and a medical expert).
  • They have voluntary control with a low to medium range of motion function (UE-FT\<5) and a muscle tone.
  • They are functionally stable (no significant changes in motor function over a week) and are able to tolerate being seated upright for 90 minutes.
  • They report no excessive pain the impaired arm.
  • If left neglect or spasticity is detected in the impaired arm, these levels must not interfere with the ability to cognitively complete the tasks or turn a wheel.
  • They must not be participating in any experimental rehabilitation or drug therapies.
  • If subjects are receiving chemical injections for spasticity, they must be at least 3-months away from their last treatment.
  • They must have driven prior to stroke.
  • They are not clinically depressed (as measured by the Geriatric Depression Scale (GDS) short form (Sheikh and Yesavage, 1986).

You may not qualify if:

  • Once informed consent is given twenty-four of these subjects will be randomized into two training groups (fun driving: fun and functional driving activities and rote tracking (12 subjects): rote and functional tracking activities). Two subjects will be randomized the case study group. The groups will be matched in initial motor function.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clement J Zablocki VA - Rehabilitation Robotics R&D Lab

Milwaukee, Wisconsin, 53295, United States

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Michelle J Johnson, PhD

    Medical College of Wisconsin

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Adjunct Associate Professor

Study Record Dates

First Submitted

October 30, 2006

First Posted

October 31, 2006

Study Start

July 1, 2006

Primary Completion

June 1, 2013

Study Completion

June 1, 2013

Last Updated

February 4, 2014

Record last verified: 2014-02

Locations