Exercise and Bright Light Treatment: Effects on Body Weight and Composition

NCT00384345 | Completed Phase 2

• 1 other identifier: 03-0184-BE
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

Bright light therapy has been used to safely and effectively treat conditions such as Seasonal Affective Disorder and to regularize sleep in patients with circadian rhythm disorder. Based on evidence of the link between bright light, serotonin, mood and carbohydrate metabolism, it has been suggested that bright light therapy can improve weight loss but the literature on the subject is sparse. Further, the literature suggests that apart from any changes in mood and carbohydrate metabolism, bright light may reduce the unpleasant side-effects of exercise and increase compliance to an exercise program.

Conditions

Obesity; Fatigue

Keywords

bright light treatment; exercise; body fat index; mood; sleep; fatigue

Outcome Measures

Primary Outcomes (1)

• The primary outcome measure will be the amount of weight loss.

Secondary Outcomes (1)

• Secondary outcome measures will be the ratings of mood on the POMS, CES-D and SPAQ

Interventions

Bright Light Therapy DEVICE

Exercise BEHAVIORAL

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Overweight subjects
• Subjects in otherwise good health
• Subjects willing to participate in a 6-week moderate exercise program
• Bedtime between 10pm and 12am; wake-up time between 6am and 8am
• Score in the median range of the Morningness/ Eveningness Questionnaire (i.e., subjects show no distinct characteristics of phase delay or phase advance)

You may not qualify if:

• Progressive eye disease
• History of cataracts, macular degeneration or have undergone laser corrective eye surgery in the past 30 days.
• Currently taking any medications, e.g. antibiotics, tricyclic antidepressants, that may affect photosensitivity
• History of heart disease
• History of respiratory diseases, such as asthma, emphysema
• Any severe or uncontrolled general medical condition
• Severe psychiatric disorder (as determined by psychiatrist - CMS)
• History of mania
• Grossly obese individuals with morbid obesity

Sponsors & Collaborators

• University Health Network, Toronto: lead
• The Litebook Company Ltd.: collaborator

Study Sites (1)

University Health Network

Toronto, Ontario, M5T 2S8, Canada

Location

MeSH Terms

Conditions

Obesity; Fatigue; Motor Activity

Interventions

Ultraviolet Therapy; Exercise

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Phototherapy; Therapeutics; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Colin M. Shapiro, MBBCh, PhD

  University Health Network, Toronto

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: October 4, 2006
• First Posted: October 6, 2006
• Study Start: September 1, 2003
• Study Completion: December 1, 2003
• Last Updated: October 6, 2006

Record last verified: 2006-07

Locations

CA (1)