NCT00381121

Brief Summary

The purpose of the study is to create a Nephrology Tissue Biobank enabling the study of kidney disease from the perspectives of epidemiology, genetics and molecular biology.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
420

participants targeted

Target at P75+ for all trials

Timeline
51mo left

Started Sep 2006

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress82%
Sep 2006Aug 2030

Study Start

First participant enrolled

September 1, 2006

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

September 26, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 27, 2006

Completed
23.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2030

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2030

Last Updated

April 24, 2025

Status Verified

April 1, 2025

Enrollment Period

23.9 years

First QC Date

September 26, 2006

Last Update Submit

April 18, 2025

Conditions

Chronic Kidney Disease

Keywords

Tissue Biobankmolecular markersmolecular pathways

Study Arms (1)

Kidney disease cohort

Individuals with a clinically indicated biopsy are recruited and/or surplus tissue that remains from past clinical interventions is obtained.

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Renal disease patients undergoing diagnostic workup

You may qualify if:

  • Men, women and children undergoing kidney and/or pancreas biopsy at the University of Michigan

You may not qualify if:

  • Individuals not willing to provide consent (for prospective biopsy)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Michigan Health System

Ann Arbor, Michigan, 48109, United States

RECRUITING

Related Publications (1)

  • Schmid H, Henger A, Kretzler M. Molecular approaches to chronic kidney disease. Curr Opin Nephrol Hypertens. 2006 Mar;15(2):123-9. doi: 10.1097/01.mnh.0000214770.11609.fb.

    PMID: 16481877BACKGROUND

Biospecimen

Retention: SAMPLES WITH DNA

Tissue, blood, urine

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Matthias Kretzler,, MD

    University of Michigan

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Chrysta Lienczewsky

CONTACT

734-764-2924boridley@med.umich.edu

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Medicine

Study Record Dates

First Submitted

September 26, 2006

First Posted

September 27, 2006

Study Start

September 1, 2006

Primary Completion (Estimated)

August 1, 2030

Study Completion (Estimated)

August 1, 2030

Last Updated

April 24, 2025

Record last verified: 2025-04

Locations

US(1)