NCT00378924

Brief Summary

In the present study, investigators intend to establish a large database of cardiovascular patients. More specifically, investigators will create a database of approximately 12,000 cardiac catheterization and heart failure patients from Emory University Hospital, the Emory Clinic, Emory University Hospital Midtown, Grady Memorial Hospital, Atlanta VA Medical Center, Organized/Planned Community Events in the Atlanta Metropolitan area, held at places of Worship, local Community Centers, shopping Malls, doctor's Offices and Health Clinics and any other miscellaneous locations, e.g. Parks, Leisure centers, Conference centers. Once the data has been collected, investigators will run a variety of statistical analyses to which will help us to learn more about the factors that cause various cardiovascular diseases such as coronary heart disease, angina, heart failure, hypertension, and stroke. The statistical analyses will also help us to understand how these diseases can be treated more effectively. By collecting a large amount of data on a large number of cardiovascular patients, investigators will be able to analyze, with a great deal of precision, those factors that influence the onset, course, and treatment of cardiovascular disease. The results of these precise analyses can then be used to help optimize clinical efforts to prevent and treat cardiovascular disease.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12,000

participants targeted

Target at P75+ for all trials

Timeline
47mo left

Started Dec 2003

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress85%
Dec 2003Apr 2030

Study Start

First participant enrolled

December 1, 2003

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

September 19, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 21, 2006

Completed
23.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2030

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2030

Last Updated

June 17, 2025

Status Verified

June 1, 2025

Enrollment Period

26.4 years

First QC Date

September 19, 2006

Last Update Submit

June 12, 2025

Conditions

Cardiovascular Disease

Outcome Measures

Primary Outcomes (1)

  • All cause death

    Continuous

Secondary Outcomes (2)

  • Cardiovascular death

    Continuous

  • Re-hospitalization for heart failure

    Continuous

Other Outcomes (2)

  • Myocardial Infarction

    Continuous

  • Stroke

    Continuous

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

General population \& patients presenting to the hospital

You may qualify if:

  • All hospital and clinic patients aged 18 years and older
  • Patients with active cardiovascular disease including but not limited to
  • Ischemic Heart Disease
  • Heart Failure and Cardiomyopathies
  • Peripheral Vascular Disease
  • Valve disease
  • Adult Congenital Heart disease
  • Electrophysiological Disorders
  • Any Atlanta metropolitan area resident aged 18 and above in satisfactory physical health and able to tolerate a blood draw or buccal swab.

You may not qualify if:

  • Significant Documented Anemia (Hemoglobin \<8 g/dL)
  • Blood transfusions within past 3 weeks
  • Active Cancer (non-skin cancers)
  • Enrollment against doctor recommendation
  • Patient not able to provide consent including but not limited to:
  • Intubated and critically unwell patients
  • Dementia
  • Alzheimer's disease
  • Moderate to severe alcohol or drug abuse
  • Against religious beliefs (e.g. Jehovah's witness

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Emory School Of Medicine

Atlanta, Georgia, 30322, United States

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

60 cc of blood will be obtained from the participant. Blood will be processed and stored in -80F freezers as plasma, serum, extracted DNA and whole blood.

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

  • Arshed A Quyyumi, MD

    Emory School Of Medicine

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ayman J Tahhan, MD

CONTACT

404 712 0168ayman.tahhan@emory.edu

Salman Sher, MD

CONTACT

404 412 0170ssher2@emory.edu

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 19, 2006

First Posted

September 21, 2006

Study Start

December 1, 2003

Primary Completion (Estimated)

April 1, 2030

Study Completion (Estimated)

April 1, 2030

Last Updated

June 17, 2025

Record last verified: 2025-06

Locations

US(1)