NCT00367666

Brief Summary

This project is aimed at investigating the relative diagnostic and synergy of four state of the art breast imaging techniques (magnetic resonance imaging (MRI), full-field digital mammography (DMAM), ultrasound, and positron emission tomography (PET)) with respect to determining the extent of breast cancer.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable breast-cancer

Timeline
10mo left

Started Mar 2002

Longer than P75 for not_applicable breast-cancer

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress97%
Mar 2002Mar 2027

Study Start

First participant enrolled

March 1, 2002

Completed
4.5 years until next milestone

First Submitted

Initial submission to the registry

August 22, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 23, 2006

Completed
20.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 12, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 12, 2027

Last Updated

March 10, 2026

Status Verified

March 1, 2026

Enrollment Period

25 years

First QC Date

August 22, 2006

Last Update Submit

March 9, 2026

Conditions

Breast Cancer

Study Arms (1)

Patients Diagnosed with Breast Cancer

EXPERIMENTAL
Device: MRI, Digital Mammography, Ultrasound and Positron Emission Tomography (PET)

Interventions

MRI, Digital Mammography, Ultrasound and Positron Emission Tomography (PET)DEVICE
Patients Diagnosed with Breast Cancer

Eligibility Criteria

Age18 Years - 80 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women recently diagnosed with Breast Cancer
  • Will be undergoing surgery (after study) at the Hospital of the University of Pennsylvania

You may not qualify if:

  • Contraindications to MRI
  • previously diagnosed with breast cancer (in the smae breast) within the past 5 years
  • Patients with known locally advanced cancer (prior to study entry) being treated with preoperative adjuvant therapy.
  • Pregnant women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

MeSH Terms

Conditions

Breast Neoplasms

Interventions

MammographyUltrasonographyPositron-Emission Tomography

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

RadiographyDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisTomography, Emission-ComputedImage Interpretation, Computer-AssistedImage EnhancementPhotographyRadionuclide ImagingTomographyDiagnostic Techniques, Radioisotope

Study Officials

  • Abass Alavi, MD

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 22, 2006

First Posted

August 23, 2006

Study Start

March 1, 2002

Primary Completion (Estimated)

March 12, 2027

Study Completion (Estimated)

March 12, 2027

Last Updated

March 10, 2026

Record last verified: 2026-03

Locations

US(1)