NCT00360633

Brief Summary

Parkinson's Disease (PD) is often thought of as affecting movement only. In fact, most patients also experience psychiatric and cognitive symptoms, sometimes from the disease itself, and sometimes as a side-effect of PD medications. The goals of this study are to evaluate the causes, effects, and clinical correlates of psychiatric and cognitive symptoms in PD.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2006

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2006

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 2, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 4, 2006

Completed
12.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 28, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 28, 2019

Completed
Last Updated

May 10, 2019

Status Verified

May 1, 2019

Enrollment Period

12.8 years

First QC Date

August 2, 2006

Last Update Submit

May 8, 2019

Conditions

Parkinson's Disease

Keywords

Parkinson's DiseaseImpulse control disorderDopamine agonist withdrawal syndromeAnxietyDepressionHealthcare UtilizationDisabilityQuality of lifeCognitive functionPsychosisApathyDyskinesiasWearing off

Outcome Measures

Primary Outcomes (1)

  • Non-motor symptom progression

    Chronic

Secondary Outcomes (1)

  • Motor symptom progression

    Chronic

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

1. Patients with Parkinson's Disease who are seen for their routine medical care at the NYU Parkinson's and Movement Disorders Center. 2. Matched healthy control subjects.

You may qualify if:

  • Diagnosis of idiopathic Parkinson's Disease (or healthy control subject)
  • Age \>=21 and \<=99
  • Capacity to provide informed consent
  • Ability to complete the questionnaires

You may not qualify if:

  • Clinical diagnosis of dementia
  • Terminal illness (life expectancy \< 12 months)
  • Presence of a neurodegenerative disorder other than Parkinson's Disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NYU School of Medicine

New York, New York, 10016, United States

Location

Related Links

MeSH Terms

Conditions

Parkinson DiseaseDisruptive, Impulse Control, and Conduct DisordersAnxiety DisordersDepressionPsychotic DisordersLethargyDyskinesias

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative DiseasesMental DisordersBehavioral SymptomsBehaviorSchizophrenia Spectrum and Other Psychotic DisordersNeurobehavioral ManifestationsNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Melissa J Nirenberg, MD, PhD

    NYU School of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 2, 2006

First Posted

August 4, 2006

Study Start

June 1, 2006

Primary Completion

March 28, 2019

Study Completion

March 28, 2019

Last Updated

May 10, 2019

Record last verified: 2019-05

Locations

US(1)