A Cognitive Behavioral Therapy of Primary Obsessions in Obsessive Compulsive Disorder

NCT00358995 | Completed

• 1 other identifier: H02-80132
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

A New Cognitive Behavioral Therapy to Target Distorted Appraisals Characteristic of Primary Obsessions in Obsessive Compulsive Disorder

Conditions

Obsessive Compulsive Disorder

Keywords

Cognitive Behavioral Therapy; Primary Obsessions; Obsessive Compulsive Disorder; Compulsive Disorder

Outcome Measures

Primary Outcomes (1)

• The primary outcome of the study is to determine if CBT is more effective than SMT in reducing distorted beliefs and OCD symptoms in study participants post treatment, as well as six and twelve months post treatment.

  12 months

Secondary Outcomes (1)

• The secondary outcome of the study is to determine if change in appraisals of intrusive thoughts will mediate symptom change during and after treatment (i.e. follow-up).

  12 months

Study Arms (2)

1

ACTIVE COMPARATOR

Cognitive Behavior Therapy (CBT) may include keeping a diary of significant events and associated feelings, thoughts and behaviors; questioning and testing cognitions, assumptions, evaluations and beliefs that might be unhelpful and unrealistic; gradually facing activities which may have been avoided; and trying out new ways of behaving and reacting and using relaxation and distraction techniques.

Behavioral: Cognitive Behavioral Therapy

2

ACTIVE COMPARATOR

Stress Management Therapy (SMT) includes relaxation, interaction, biofeedback, exercises, such as muscle stretching exercises, yoga, meditation, time management techniques, and many more.

Behavioral: Stress Management Therapy (SMT)

Interventions

Cognitive Behavioral Therapy BEHAVIORAL

Participants will be randomly assigned to either immediate treatment or delayed treatment (three month delay). Participants will then be again be randomly assigned to either Cognitive Behavior Therapy (CBT) or Stress Management Therapy (SMT). The delayed participants (wait list control) will be randomly assigned to either of the two active treatment groups in three months time. Both active treatment conditions involve one hours, individual treatment sessions for 12 consecutive weeks by one of the treating psychologists. All participants will also be asked to complete a package of psychometric questionnaires before treatment.

1

Stress Management Therapy (SMT) BEHAVIORAL

Participants will be randomly assigned to either immediate treatment or delayed treatment (three month delay). Participants will then be again be randomly assigned to either Cognitive Behavior Therapy (CBT) or Stress Management Therapy (SMT). The delayed participants (wait list control) will be randomly assigned to either of the two active treatment groups in three months time. Both active treatment conditions involve one hours, individual treatment sessions for 12 consecutive weeks by one of the treating psychologists. All participants will also be asked to complete a package of psychometric questionnaires before treatment.

2

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• involves:
• a primary diagnosis of OCD,
• an absence of overt compulsions associated with the primary obsessions,
• functional impairment due to OCD for at least one year,
• age range 18-65 years,
• fluency in spoken and written English,
• a willingness to undergo random assignment to treatment, and to complete the assigned treatment and planned assignments.

You may not qualify if:

• presence of a severe depressive disorder with suicidal intent requiring immediate intervention,
• evidence of organic mental disorder, active thought disorder, current alcohol or drug dependence, or mental retardation,
• concurrent psychological treatment for any axis (i) or (ii) disorder, aside from supportive therapy for depression, and
• commencement or change in psychotropic medication in the three months prior to initial assessment through to post-treatment assessment.

Sponsors & Collaborators

• University of British Columbia: lead

Study Sites (1)

UBC Hospital, The Anxiety Disorders Clinic

Vancouver, British Columbia, Canada

Location

MeSH Terms

Conditions

Obsessive-Compulsive Disorder; Compulsive Personality Disorder

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Anxiety Disorders; Mental Disorders; Personality Disorders

Intervention Hierarchy (Ancestors)

Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Peter McLean, MD

  The University of British Columbia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 28, 2006
• First Posted: August 1, 2006
• Study Start: July 1, 2002
• Primary Completion: September 1, 2007
• Study Completion: September 1, 2007
• Last Updated: February 19, 2014

Record last verified: 2014-02

Locations

CA (1)