NCT00355732

Brief Summary

To evaluate and compare two methods of weaning from mechanical ventilation in patients with chronic obstructive pulmonary disease (COPD) where the extubation failed.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 23, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 25, 2006

Completed
Last Updated

October 26, 2006

Status Verified

July 1, 2006

First QC Date

July 23, 2006

Last Update Submit

October 25, 2006

Conditions

Respiratory Failure

Keywords

RespirationCOPDMechanical VentilationVentilator WeaningRespiratory FailureICUPressure Support Ventilation

Interventions

Weaning from mechanical ventilationPROCEDURE

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • COPD
  • exacerbation of dyspnea \<2 weeks
  • signs of respiratory muscle dysfunction

You may not qualify if:

  • non COPD patients
  • age \<18 years
  • tracheotomy
  • MV duration shorter than 24h
  • use of MV on admission to the ICU or transfer to some other ICU for treatment continuation
  • patients who died or weaning from MV was discontinued because of another associated disorder
  • central nerve system disorders unrelated to hypercapnic encephalopathy or hypoxemia
  • cardiac arrest within 5 days
  • patients scheduled for organ donation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Dr. Josip Benčević General Hospital

Slavonski Brod, 35000, Croatia

Location

Clinic Hospital Center Zagreb

Zagreb, 10000, Croatia

Location

MeSH Terms

Conditions

Respiratory InsufficiencyRespiratory AspirationPulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsLung Diseases, ObstructiveLung DiseasesChronic DiseaseDisease Attributes

Study Officials

  • Ivo Matić, MD PhD

    Department of Anesthesiology and Intensive Care, Dr. Josip Benčević General Hospital, Slavonski Brod, Croatia

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 23, 2006

First Posted

July 25, 2006

Last Updated

October 26, 2006

Record last verified: 2006-07

Locations

CR(2)