NCT00351676

Brief Summary

We, the researchers, propose to link a clinical pharmacist with an internal medicine or family medicine team to provide pharmaceutical care to all patients assigned to the team. The hypothesis is that through this team based approach, pharmacists will act as a resource for providing pharmacotherapeutic advice during the drug therapy decision making process and promote optimal drug use by identifying and resolving actual and potential drug related problems. This study is designed to test this hypothesis, by assessing the impact of this intervention on evidence based, quality of drug therapy indicators, for patients admitted with heart failure (HF), chronic obstructive pulmonary disease (COPD), community acquired pneumonia (CAP), type 2 diabetes mellitus (T2DM), and stable coronary artery disease (CAD).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
452

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Feb 2006

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2006

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

July 12, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 13, 2006

Completed
12 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2007

Completed
Last Updated

December 11, 2007

Status Verified

February 1, 2006

First QC Date

July 12, 2006

Last Update Submit

December 7, 2007

Conditions

Heart Failure, CongestivePulmonary Disease, Chronic ObstructivePneumoniaDiabetes Mellitus, Type 2Coronary Arteriosclerosis

Keywords

Drug TherapyHospitals, TeachingHospitals, CommunityInterprofessional relationsPatient Care TeamPharmacistsPharmacy Service, HospitalComparative StudyHospitalization

Outcome Measures

Primary Outcomes (1)

  • Improvement in proportion of quality indicators achieved, for target diseases as a most responsible or primary diagnosis, between groups.

    in hospital

Secondary Outcomes (4)

  • Differences in condition-specific achievement of drug therapy quality indicators;

    in hospital

  • Differences in 6 month hospital readmission rate;

    6 months

  • Differences in number, type, acceptance rate, and expected impact of all pharmacist interventions;

    in hospital

  • Qualitative evaluation of the impact of the intervention via interviews with the participating pharmacists and physicians.

    in hospital

Interventions

Integration of a team based clinical pharmacistBEHAVIORAL
Optimizing therapeutic treatmentsDRUG
Optimizing processes of careBEHAVIORAL

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Consecutive patients \> 18 years of age admitted to participating internal and family medicine teams during the 1 year study period will be eligible to receive the pharmacist intervention. For the purposes of data analysis, patients with a most responsible or primary diagnosis of HF, COPD, CAP, T2DM, and CAD will be included.

You may not qualify if:

  • Residence outside the Capital Health catchment
  • Admitted for ≤ 2 days
  • Palliative care
  • Transferred to another team

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Royal Alexandra Hospital

Edmonton, Alberta, T5H 3V9, Canada

Location

University of Alberta Hospital

Edmonton, Alberta, T6G 2B7, Canada

Location

Grey Nuns Community Hospital

Edmonton, Alberta, T6L 5X8, Canada

Location

Related Publications (2)

  • Makowsky MJ, Koshman SL, Midodzi WK, Tsuyuki RT. Capturing outcomes of clinical activities performed by a rounding pharmacist practicing in a team environment: the COLLABORATE study [NCT00351676]. Med Care. 2009 Jun;47(6):642-50. doi: 10.1097/MLR.0b013e3181926032.

    PMID: 19433997DERIVED

  • Makowsky MJ, Schindel TJ, Rosenthal M, Campbell K, Tsuyuki RT, Madill HM. Collaboration between pharmacists, physicians and nurse practitioners: a qualitative investigation of working relationships in the inpatient medical setting. J Interprof Care. 2009 Mar;23(2):169-84. doi: 10.1080/13561820802602552.

    PMID: 19234987DERIVED

Related Links

MeSH Terms

Conditions

Heart FailurePulmonary Disease, Chronic ObstructivePneumoniaDiabetes Mellitus, Type 2Coronary Artery Disease

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsRespiratory Tract InfectionsInfectionsDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesCoronary DiseaseMyocardial IschemiaArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Officials

  • Ross T. Tsuyuki, PharmD, MSc

    University of Alberta

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NON RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 12, 2006

First Posted

July 13, 2006

Study Start

February 1, 2006

Study Completion

July 1, 2007

Last Updated

December 11, 2007

Record last verified: 2006-02

Locations

CA(3)