NCT00349869

Brief Summary

The purpose of this study is to evaluate the impact of yoga on inflammatory arthritis and knee osteoarthritis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for not_applicable rheumatoid-arthritis

Timeline
Completed

Started Aug 2006

Longer than P75 for not_applicable rheumatoid-arthritis

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 6, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 10, 2006

Completed
22 days until next milestone

Study Start

First participant enrolled

August 1, 2006

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2010

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2011

Completed
Last Updated

June 18, 2023

Status Verified

June 1, 2023

Enrollment Period

4 years

First QC Date

July 6, 2006

Last Update Submit

June 14, 2023

Conditions

Rheumatoid ArthritisOsteoarthritis

Keywords

inflammatory arthritisrheumatoid arthritisknee osteoarthritisarthritisyoga

Outcome Measures

Primary Outcomes (1)

  • Physical Health

    Assessed using SF36 Physical Component Score

    baseline, post intervention, follow-up

Secondary Outcomes (4)

  • Mobility/Fitness

    baseline, posttest, follow-up

  • RA Disease Activity

    baseline, post intervention, follow-up

  • Psychological Function

    baseline, , posttest, follow-up

  • HRQL

    baseline, post intervention, follow-up

Study Arms (2)

1

EXPERIMENTAL

8-week yoga program

Behavioral: yoga

2

NO INTERVENTION

Usual care control

Interventions

yogaBEHAVIORAL

8-week yoga program.

1

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18+ (RA only upper age limit 70)
  • Confirmed or probable OA (using pre-specified criteria) OR Rheumatoid arthritis (participation approved by rheumatologist)
  • Currently sedentary (physically active for 20 min \< 3times/week)

You may not qualify if:

  • Inability to ambulate without use of assistive device
  • Uncontrolled high blood pressure or existing heart condition
  • Co-morbid inflammatory condition with overlapping symptoms (i.e., fibromyalgia)
  • Surgery within 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Johns Hopkins Arthritis Center, 5501 Hopkins-Bayview Circle, Ste 1B.14

Baltimore, Maryland, 21224, United States

Location

Related Publications (5)

  • Bartlett SJ, Moonaz SH, Mill C, Bernatsky S, Bingham CO 3rd. Yoga in rheumatic diseases. Curr Rheumatol Rep. 2013 Dec;15(12):387. doi: 10.1007/s11926-013-0387-2.

    PMID: 24173693RESULT

  • Haaz S, Bartlett SJ. Yoga for arthritis: a scoping review. Rheum Dis Clin North Am. 2011 Feb;37(1):33-46. doi: 10.1016/j.rdc.2010.11.001. Epub 2010 Dec 3.

    PMID: 21220084RESULT

  • Haaz S, Bingham CO, Bathon JM, Bartlett SJ. The effect of yoga on clinical parameters in patients with rheumatoid arthritis. Arthritis & Rheumatism 2008;58:S893-S4.

    RESULT

  • Haaz S, Bingham III CO, Bartlett SJ. Adherence to an 8-week yoga program for RA and OA: Who drops out and why? Arthritis & Rheumatism 2009;60:1978.

    RESULT

  • Moonaz SH, Bingham CO 3rd, Wissow L, Bartlett SJ. Yoga in Sedentary Adults with Arthritis: Effects of a Randomized Controlled Pragmatic Trial. J Rheumatol. 2015 Jul;42(7):1194-202. doi: 10.3899/jrheum.141129. Epub 2015 Apr 1.

    PMID: 25834206RESULT

Related Links

MeSH Terms

Conditions

Arthritis, RheumatoidOsteoarthritisArthritisOsteoarthritis, Knee

Interventions

Yoga

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsSpiritual TherapiesExercise Movement TechniquesPhysical Therapy Modalities

Study Officials

  • Susan J. Bartlett, Ph.D.

    Associate Professor of Medicine, Johns Hopkins Rheumatology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Assessors masked to study condition
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized controlled trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 6, 2006

First Posted

July 10, 2006

Study Start

August 1, 2006

Primary Completion

August 1, 2010

Study Completion

August 1, 2011

Last Updated

June 18, 2023

Record last verified: 2023-06

Locations

US(1)