NCT00349323

Brief Summary

The WHO Special Programme for Research and Training in Tropical Diseases (TDR) developed a Community-Directed Treatment (COMDT) approach, which has been adopted in the control of onchocerciasis and lymphatic filariasis. WHO has recommended the use of COMDT approach in the control of schistosomiasis and STH infections. The COMDT approach has been compared with the school based programmes in certain African countries,but not with the health-facility based approach. The project will be implemented in Mazabuka district of Zambia where COMDT approach will be implemented in the catchment area of Rural Health Centres (RHC) as a supplement to the health-facility-based approach. After each round of treatmenttreatment coverage and factors responsible for the treatment coverage will be measured in both areas. The health impact of the health facility based approach with and without the COMDT approach will be compared. The effect of the COMDT as a control approach of STH infections will be monitored on infections in the community of children aged 12 to 59 months.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Aug 2006

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 6, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 7, 2006

Completed
25 days until next milestone

Study Start

First participant enrolled

August 1, 2006

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2007

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2007

Completed
Last Updated

May 8, 2008

Status Verified

February 1, 2008

Enrollment Period

1 year

First QC Date

July 6, 2006

Last Update Submit

May 7, 2008

Conditions

Soil-Transmitted Helminth InfectionGrowth

Keywords

Community directed treatment,soil-transmitted helminth infections,treatment coverage,Zambia

Interventions

Community directed treatmentBEHAVIORAL

Eligibility Criteria

Age12 Months - 59 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Age 12-59 months

You may not qualify if:

  • Severely ill children

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mazabuka District

Mazabuka, Zambia

Location

Related Publications (1)

  • Halwindi H, Magnussen P, Meyrowitsch D, Handema R, Siziya S, Olsen A. Effect on treatment coverage of adding community-directed treatment to the health facility-based approach of delivering anthelminthic drugs to under-five children during child health week in Mazabuka District, Zambia. Int Health. 2010 Dec;2(4):253-61. doi: 10.1016/j.inhe.2010.09.003.

    PMID: 24037866DERIVED

Study Officials

  • Hikabasa Halwindi, M.phil

    Department of Community Medicine, University of Zambia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 6, 2006

First Posted

July 7, 2006

Study Start

August 1, 2006

Primary Completion

August 1, 2007

Study Completion

September 1, 2007

Last Updated

May 8, 2008

Record last verified: 2008-02

Locations

ZA(1)