NCT00347789

Brief Summary

Transconjunctival mitomycin-C in needle bleb revision may be an effective procedure to treat cases with a previously failed trabeculectomy. We will investigate approximately 100 consecutive cases with follow up of up to 9 years. We anticipate that this procedure is an effective, safe, and appropriate option for successful glaucoma treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 1997

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 1997

Completed
9.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2006

Completed
29 days until next milestone

First Submitted

Initial submission to the registry

June 30, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 4, 2006

Completed
Last Updated

July 4, 2006

Status Verified

June 1, 2006

First QC Date

June 30, 2006

Last Update Submit

June 30, 2006

Conditions

Glaucoma

Keywords

glaucomatrabeculectomyfiltering bleb revisionintraocular pressureneedling proceduremitomycin C

Interventions

Glaucoma surgery- Bleb revisionPROCEDURE

Eligibility Criteria

Age0 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of glaucoma
  • Failed filtering procedures- defined as intraocular pressure exceeded target pressure thus inducing possible further optic nerve damage

You may not qualify if:

  • \- Needling combined with other ocular surgical or laser treatments

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Glaucoma Center of San Francisco

San Francisco, California, 94105, United States

Location

MeSH Terms

Conditions

Glaucoma

Condition Hierarchy (Ancestors)

Ocular HypertensionEye Diseases

Study Officials

  • Andrew G. Iwach, MD

    Glaucoma Reseach & Education Group

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
DEFINED POPULATION
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 30, 2006

First Posted

July 4, 2006

Study Start

May 1, 1997

Study Completion

June 1, 2006

Last Updated

July 4, 2006

Record last verified: 2006-06

Locations

US(1)