Optical Coherence Tomography of Retinal Abnormalities Associated With Choroidal Nevus, Choroidal Melanoma and Choroidal Melanoma Treated With Iodine-125 Brachytherapy

NCT00346372 | Terminated

• 1 other identifier: UCLA IRB#03-11-052
• Study Type: observational
• Target: 5
• Locations: 1 country
• Sites: 1

Brief Summary

During regularly scheduled appointments, Optical Coherence Tomography (OCT) is performed on consented subjects. The OCT is a new type of camera that takes very detailed pictures inside of the eye and deeper into eye tissues. Optical Coherence Tomography imaging of intraocular tumors may lead to improved diagnosis and monitoring of tumors within the eye.

Conditions

Ocular Melanoma

Keywords

Ocular Melanoma; Optical Coherence Tomography; Eye Tumor; Choroidal Melanoma; Uveal Melanoma

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who meet the following Eligibility Criteria

You may qualify if:

• Adults (18 years or older) with:
• choroidal nevus greater than or equal to 3.0 mm in longest basal diameter, or greater than or equal to 1.25 mm in apical height or:
• choroidal melanoma located in the posterior pole (4mm or less from the center of fovea or the border of the optic nerve head)

You may not qualify if:

• Ocular media opacity in the tumor eye that prevents adequate functional testing or imaging and prior or concurrent retinal or choroidal disease in the tumor eye that prevents adequate functional testing or imaging

Sponsors & Collaborators

• Jonsson Comprehensive Cancer Center: lead

Study Sites (1)

Jules Stein Eye Institute

Los Angeles, California, 90095, United States

Location

MeSH Terms

Conditions

Uveal Melanoma; Eye Neoplasms

Condition Hierarchy (Ancestors)

Melanoma; Neuroendocrine Tumors; Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Nerve Tissue; Nevi and Melanomas; Uveal Neoplasms; Neoplasms by Site; Eye Diseases; Uveal Diseases

Study Officials

• Bradley R Straatsma, MD, JD

  Jules Stein Eye Institute, UCLA

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 27, 2006
• First Posted: June 29, 2006
• Study Start: March 1, 2004
• Primary Completion: November 27, 2017
• Study Completion: November 27, 2017
• Last Updated: August 12, 2019

Record last verified: 2018-01

Locations

US (1)