Key Insights

Highlights

Success Rate

93% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

3.6%

1 terminated out of 28 trials

Success Rate

93.3%

+6.8% vs benchmark

Late-Stage Pipeline

7%

2 trials in Phase 3/4

Results Transparency

36%

5 of 14 completed with results

Key Signals

5 with results93% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (2)
P 1 (6)
P 2 (10)
P 3 (2)

Trial Status

Completed14
Recruiting5
Unknown4
Active Not Recruiting2
Withdrawn2
Terminated1

Trial Success Rate

93.3%

Benchmark: 86.5%

Based on 14 completed trials

Clinical Trials (28)

Showing 20 of 20 trials
NCT05187884Phase 2CompletedPrimary

Neoadjuvant/Adjuvant Trial of Darovasertib in Ocular Melanoma

NCT05628883Phase 1Completed

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

NCT05524935Phase 2Recruiting

Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma

NCT06861647Completed

iSITE: Investigation of Somatic Alterations in Tumours of the Eye

NCT02858869Phase 1Completed

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

NCT06007690Phase 3Recruiting

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

NCT07421739Recruiting

Choroidal Melanoma Patient-Reported Outcome Study (CM-PRO) in a Subset of AU-011-301 (CoMpass) Subjects

NCT06432660Active Not RecruitingPrimary

Eye Plaque Brachytherapy for Ocular Melanoma

NCT06717126Phase 2Active Not Recruiting

A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma

NCT06940739Phase 1Recruiting

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

NCT06970236Not ApplicableRecruitingPrimary

Resistance Exercise in Patients With Ocular Melanoma

NCT01355120Phase 2CompletedPrimary

THE IPI - Trial in Advanced Melanoma: Melanoma Patients With Advanced Disease

NCT03172299Phase 3CompletedPrimary

Prevention of Neovascular Glaucoma by Intravitreal Injections of Anti-VEGF in Patients Treated with Proton Therapy for a Large Choroidal Melanoma

NCT04417530Phase 2Completed

Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

NCT04364230Phase 1Completed

Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma)

NCT02519322Phase 2Completed

Neoadjuvant and Adjuvant Checkpoint Blockade

NCT03052127Phase 1Completed

Study in Subjects With Small Primary Choroidal Melanoma

NCT03528408Phase 2Unknown

Study of Adjuvant Ipilimumab and Nivolumab in Subjects With High-risk Ocular Melanoma

NCT01930968WithdrawnPrimary

Definity for Ultrasound of Intraocular Tumors

NCT02129075Phase 2Completed

A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma

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