NCT00344656

Brief Summary

This study will use functional magnetic resonance imaging to compare appetite-related brain activity in women with anorexia nervosa before and after receiving treatment for the disorder.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Oct 2004

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2004

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

June 23, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 27, 2006

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2010

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2010

Completed
Last Updated

April 19, 2012

Status Verified

April 1, 2012

Enrollment Period

5.5 years

First QC Date

June 23, 2006

Last Update Submit

April 18, 2012

Conditions

Eating DisordersAnorexia Nervosa

Keywords

Eating DisordersAnorexia Nervosa

Study Arms (1)

Subjects and Controls

Patients with DSM-IV Anorexia Nervosa

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Women with AN between 18 and 45 years of age hospitalized for treatment of anorexia nervosa.

You may qualify if:

  • For Participants with AN:
  • DSM-IV diagnosis of AN (restricting or binge eating/purging subtype)
  • Medically stable (not continuing to lose weight and vital signs stable)
  • For Healthy Participants:
  • Currently weighs 80-120% of ideal weight
  • no history of binge eating disorder or vomiting
  • no current or past psychiatric illness

You may not qualify if:

  • For Participants with AN:
  • Currently taking medication
  • Current substance abuse or dependence disorder
  • History of suicide attempt or other self-injurious behavior within 6 months prior to study entry
  • Non-removable metal on or inside the body (e.g., metal pacemaker, surgical clips, metallic-ink tattoos)
  • For Healthy Participants:
  • Current or past psychiatric illness
  • History of binge eating or vomiting
  • Any significant medical or neurologic illness
  • Currently taking medication
  • History of drug or alcohol abuse within 3 months prior to study entry
  • Non-removable metal on or inside the body (e.g., metal pacemaker, surgical clips, metallic-ink tattoos)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York State Psychiatric Institute

New York, New York, 10032, United States

Location

MeSH Terms

Conditions

Feeding and Eating DisordersAnorexia Nervosa

Condition Hierarchy (Ancestors)

Signs and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and SymptomsMental Disorders

Study Officials

  • Laurel Mayer, MD

    New York State Psychiatric Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 23, 2006

First Posted

June 27, 2006

Study Start

October 1, 2004

Primary Completion

April 1, 2010

Study Completion

October 1, 2010

Last Updated

April 19, 2012

Record last verified: 2012-04

Locations

US(1)