NCT00340847|Completed
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Sponsor study identifier
Secondary identifiers
observational
500
1 country
1
Study Start
August 9, 2001
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
May 19, 2010
Date type not reportedThis date has not been verified as actual or estimated.
The proposed research intends to construct a set of tissue microarrays containing different types of normal and lung cancer tissues for the study of genes associated with lung cancer. Thus far we have generated a lung cancer tissue arrayusing paraffin embedded archival tissues from 300 lung turmors tissues and 100 adjacent normal tissues. Four- micrometer thickness sections have been cut from the tissue array and were used to survey gene expression status in arrayed tumors using immunohistochemistry methody. We are currently performing IHC studies ot 1) determine protein expression and its correlation with gene expression patterms ovserved using cDNA arrays. 2) Analyze protein expression in the chromosome remodeling pathyway in non-small cell lung cancer. And 3) determine the association of gene expression with lung tumor stage and clinical outcome. The current protocol is needed to complete the above studies and for the production of neuroendocrine tumors.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 19, 2010
Date type not reportedThis date has not been verified as actual or estimated.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 9, 2001
Date type not reportedThis date has not been verified as actual or estimated.
June 19, 2006
Actual (reported)June 21, 2006
Actual (reported)May 19, 2010
Date type not reportedThis date has not been verified as actual or estimated.
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National Cancer Institute (NCI), 9000 Rockville Pike
Bethesda, Maryland, 20892, United States
First Submitted
June 19, 2006
First Posted
June 21, 2006
Study Start
August 9, 2001
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
May 19, 2010
Date type not reportedThis date has not been verified as actual or estimated.
Genetic Epidemiology of Lung Cancer and Smoking
Last Updated
July 2, 2017
Record last verified: 2010-05-19
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