NCT00333905

Brief Summary

The purpose of this study is to determine if reducing blood flow to an exercising muscle during exercise training will enhance the training effect on that muscle in people who have limited exercise because of congestive heart failure

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable heart-failure

Timeline
Completed

Started Mar 2006

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2006

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 2, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 6, 2006

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2008

Completed
Last Updated

February 5, 2009

Status Verified

June 1, 2006

First QC Date

June 2, 2006

Last Update Submit

February 3, 2009

Conditions

Heart FailureCongestive Heart FailureCardiovascular Disease

Keywords

ExerciseExercise Therapy

Outcome Measures

Primary Outcomes (1)

  • Exercise duration before and after 12 weeks of training during a submaximal exercise test and distance walked on a 6-minute walk test.

Secondary Outcomes (1)

  • Peak cycle ergometer VO2max test before and after training

Interventions

Ischemic exercise trainingPROCEDURE

Eligibility Criteria

Age30 Years - 71 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Mild Congestive Heart Failure
  • Must be able to exercise

You may not qualify if:

  • Venous or arterial thrombus
  • Lower extremity arthritis
  • Blood clotting abnormalities
  • Claudication
  • Peripheral vascular disease
  • Evidence of deep vein thrombosis on ultrasound

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New Mexico VA Health Care System

Albuquerque, New Mexico, 87108, United States

Location

Related Publications (1)

  • Loeppky JA, Gurney B, Kobayashi Y, Icenogle MV. Effects of ischemic training on leg exercise endurance. J Rehabil Res Dev. 2005 Jul-Aug;42(4):511-22. doi: 10.1682/jrrd.2004.06.0069.

    PMID: 16320146BACKGROUND

MeSH Terms

Conditions

Heart FailureCardiovascular DiseasesMotor Activity

Condition Hierarchy (Ancestors)

Heart DiseasesBehavior

Study Officials

  • Milton V Icenogle, MD

    Cardiology Division Chief, Medicine Service VAMC Albuquerque (501) Albuquerque, NM

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED

Study Record Dates

First Submitted

June 2, 2006

First Posted

June 6, 2006

Study Start

March 1, 2006

Study Completion

February 1, 2008

Last Updated

February 5, 2009

Record last verified: 2006-06

Locations

US(1)