NCT00330213

Brief Summary

Red wine consumption is associated with reduced cardiovascular disease mortality, and the cardioprotective properties may be partly related to its ability to improve endothelial function. The purpose of this study was to determine whether moderate doses of red wine, de-alcoholized red wine and cognac improve coronary flow reserve.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Oct 2004

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2004

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2005

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

May 24, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 26, 2006

Completed
Last Updated

May 26, 2006

Status Verified

September 1, 2004

First QC Date

May 24, 2006

Last Update Submit

May 24, 2006

Conditions

Healthy

Keywords

transthoracicechocardiographyred winecognaccoronary reactivity

Outcome Measures

Primary Outcomes (2)

  • coronary flow reserve

  • plasma antioxidant capacity

Interventions

red wine and cognac consumptionBEHAVIORAL

Eligibility Criteria

Age18 Years - 70 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • healthy males

You may not qualify if:

  • smoking, medication of any kind

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept. Clinical Physiology and Nuclear Medicine, Turku University Hospital

Turku, FIN-20520, Finland

Location

Related Publications (2)

  • Kiviniemi TO, Saraste M, Koskenvuo JW, Airaksinen KE, Toikka JO, Saraste A, Parkka JP, Hartiala JJ. Coronary artery diameter can be assessed reliably with transthoracic echocardiography. Am J Physiol Heart Circ Physiol. 2004 Apr;286(4):H1515-20. doi: 10.1152/ajpheart.00819.2003. Epub 2003 Dec 4.

    PMID: 14656707BACKGROUND

  • Kiviniemi TO, Saraste A, Toikka JO, Saraste M, Raitakari OT, Parkka JP, Lehtimaki T, Hartiala JJ, Viikari J, Koskenvuo JW. Effects of cognac on coronary flow reserve and plasma antioxidant status in healthy young men. Cardiovasc Ultrasound. 2008 Jun 3;6:25. doi: 10.1186/1476-7120-6-25.

    PMID: 18522727DERIVED

Study Officials

  • Tuomas O Kiviniemi, MD

    Dept. Clinical Physiology and Nuclear Medicine, Turku University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 24, 2006

First Posted

May 26, 2006

Study Start

October 1, 2004

Study Completion

April 1, 2005

Last Updated

May 26, 2006

Record last verified: 2004-09

Locations

FI(1)