NCT00329277

Brief Summary

Standard perimetry provides information on topographical retinal sensitivity to light stimuli, however the said locus is not necessarily the preferred locus for fixation. Standard perimetry could also be used as a way for macular scotoma mapping, indirectly showing the fixation locus. Topographic acuity at the preferred retinal locus can be determined if correlation between loci with high sensitivity, eccentric fixation loci and potential visual acuity measurements are correlated. PURPOSE OF THE STUDY: Determination of visual acuity at preferred retinal locus in Low Vision patients with ARMD using eye standard automated and computerized perimetry methods.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2006

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2006

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

May 23, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 24, 2006

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2008

Completed
Last Updated

May 28, 2008

Status Verified

November 1, 2006

Enrollment Period

1.8 years

First QC Date

May 23, 2006

Last Update Submit

May 22, 2008

Conditions

Age-Related Macular Degeneration

Keywords

age-related macular degenerationpreferred retinal locusmacular perimetry

Outcome Measures

Primary Outcomes (1)

  • Location of eccentric retinal locus of highest fixation accuracy

Secondary Outcomes (1)

  • Location of eccentric locus with best retinal sensitivity

Interventions

perimetryPROCEDURE

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • AMD with documented pathology
  • Low Vision both eyes
  • BCVA 20/50-20/400 in best eye

You may not qualify if:

  • Cognitive impairment
  • Other retinal pathology
  • Previous retinal surgery
  • Significant media opacity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dr S N Markowitz

Toronto, Ontario, M6H 2H1, Canada

Location

MeSH Terms

Conditions

Macular Degeneration

Condition Hierarchy (Ancestors)

Retinal DegenerationRetinal DiseasesEye Diseases

Study Officials

  • Samuel Markowitz, MD

    University Health Network, Toronto

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 23, 2006

First Posted

May 24, 2006

Study Start

April 1, 2006

Primary Completion

January 1, 2008

Study Completion

January 1, 2008

Last Updated

May 28, 2008

Record last verified: 2006-11

Locations

CA(1)