NCT00328640

Brief Summary

Is a secondary prevention intervention, focused on implementation of standardized pre-printed discharge orders for hospitalists, effective at increasing utilization of the following evidence-based treatments 6 months after discharge for ischemic stroke:

  1. 1.Treatment with statins,
  2. 2.Control of hypertension, and
  3. 3.Anticoagulation in patients with atrial fibrillation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Dec 2005

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2005

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

May 18, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 22, 2006

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2007

Completed
Last Updated

April 27, 2007

Status Verified

April 1, 2007

First QC Date

May 18, 2006

Last Update Submit

April 25, 2007

Conditions

Ischemic Stroke

Keywords

CVAIschemic stroke

Outcome Measures

Primary Outcomes (3)

  • Medication utilization

  • Best Practices

  • Recurrent stroke

Secondary Outcomes (4)

  • Mortality

  • Morbidity

  • Cost

  • Hospital readmission

Interventions

Optimal treatmentDRUG

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Ischemic stroke Kaiser-Permanente Health Plan Member with Pharmacy Benefit Discharged alive to home

You may not qualify if:

  • tpA patients Hemorrhagic stroke TIA Significant comorbidities

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kaiser-Permanente Division of Research

Oakland, California, 94612, United States

Location

Related Publications (1)

  • Johnston SC, Sidney S, Hills NK, Grosvenor D, Klingman JG, Bernstein A, Levin E. Standardized discharge orders after stroke: results of the quality improvement in stroke prevention (QUISP) cluster randomized trial. Ann Neurol. 2010 May;67(5):579-89. doi: 10.1002/ana.22019.

    PMID: 20437555DERIVED

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

StrokeCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • David M Grosvenor, MPH

    University of California, San Francisco

    STUDY DIRECTOR

  • S C Johnston, MD

    University of California, San Francisco

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 18, 2006

First Posted

May 22, 2006

Study Start

December 1, 2005

Study Completion

March 1, 2007

Last Updated

April 27, 2007

Record last verified: 2007-04

Locations

US(1)