NCT00313326

Brief Summary

This is a comparative study of duration of respiratory weaning between adaptive support ventilation and succession of controlled ventilation then spontaneous ventilation for patients after surgery.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
66

participants targeted

Target at below P25 for phase_3

Timeline
Completed

Started Feb 2005

Shorter than P25 for phase_3

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2005

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2005

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2005

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

April 11, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 12, 2006

Completed
Last Updated

October 8, 2008

Status Verified

October 1, 2008

Enrollment Period

7 months

First QC Date

April 11, 2006

Last Update Submit

October 7, 2008

Conditions

Ventilator Weaning

Keywords

Adaptive Support ventilationWeaning

Outcome Measures

Primary Outcomes (1)

  • Duration of weaning

    duration

Secondary Outcomes (1)

  • Memorizing of weaning

    memorizing

Interventions

Adaptative Support VentilationPROCEDURE

Adaptive Support Ventilation (ASV) is a new protocol of weaning of the tracheal prosthesis after surgery which maintains a preset ventilation by an operator, and this whatever the activity of the patient

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Surgery \< 2 hours
  • Anesthesia with thiopental, midazolam, sufentanil and suprane

You may not qualify if:

  • Patients ASA III or IV (classification of American Sociéty of Anesthésiologist)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clermont-Ferrand University Hospital

Clermont-Ferrand, 63000, France

Location

Related Publications (2)

  • Petter AH, Chiolero RL, Cassina T, Chassot PG, Muller XM, Revelly JP. Automatic "respirator/weaning" with adaptive support ventilation: the effect on duration of endotracheal intubation and patient management. Anesth Analg. 2003 Dec;97(6):1743-1750. doi: 10.1213/01.ANE.0000086728.36285.BE.

    PMID: 14633553BACKGROUND

  • Sulzer CF, Chiolero R, Chassot PG, Mueller XM, Revelly JP. Adaptive support ventilation for fast tracheal extubation after cardiac surgery: a randomized controlled study. Anesthesiology. 2001 Dec;95(6):1339-45. doi: 10.1097/00000542-200112000-00010.

    PMID: 11748389BACKGROUND

Study Officials

  • Eric Schneider, Doctor

    University Hospital, Clermont-Ferrand

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 11, 2006

First Posted

April 12, 2006

Study Start

February 1, 2005

Primary Completion

September 1, 2005

Study Completion

September 1, 2005

Last Updated

October 8, 2008

Record last verified: 2008-10

Locations

FR(1)