NCT00310310

Brief Summary

Obstructive sleep apnea syndrome (OSA) is a common sleep disorder that is associated with serious medical and psychological complications. Nasal continuous positive airway pressure (CPAP) is the treatment of choice for this condition because it is highly effective in reducing the frequency of nocturnal respiratory events, improving sleep architecture, decreasing daytime sleepiness and improving blood pressure. Incomplete patient adherence, however, limits the effectiveness of CPAP therapy and results in sub-optimal patient outcomes. Previous efforts to enhance CPAP adherence have resulted in only modest improvements, have generally not been theory-driven, and have had minimal effects on key patient outcomes such as reduction in OSA symptoms or increase in health-related quality of life (HRQOL). The planned intervention in this proposal, the Sleep Apnea Self-Management Program (SASMP), is based on the rationale that sleep apnea is a chronic disease that requires significant self-care on the part of the patient. We draw on the extensive chronic disease self-management literature to provide a solid theoretical justification for this pragmatic intervention both to better manage key aspects of OSA and to increase CPAP adherence. Chronic disease management programs help reduce symptoms, improve HRQOL, improve treatment adherence, and decrease medical utilization.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
240

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Apr 2006

Typical duration for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 30, 2006

Completed
2 days until next milestone

Study Start

First participant enrolled

April 1, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 3, 2006

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2009

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
7.3 years until next milestone

Results Posted

Study results publicly available

March 22, 2017

Completed
Last Updated

April 20, 2017

Status Verified

March 1, 2017

Enrollment Period

3.1 years

First QC Date

March 30, 2006

Results QC Date

December 23, 2014

Last Update Submit

March 22, 2017

Conditions

Keywords

Continuous positive airway pressurePatient complianceSelf-care

Outcome Measures

Primary Outcomes (2)

  • CPAP Adherence

    The investigators examined the data obtained in the Sleep Apnea Self-Management Program at the one-month time point relative to participation in the Usual Care group.

    1 month

  • CPAP Adherence

    The investigators also examined the data obtained at the 6-month time point.

    6 months

Secondary Outcomes (2)

  • Pittsburgh Sleep Quality Index (PSQI)

    1 Month

  • Pittsburgh Sleep Quality Index (PSQI)

    6 Months

Other Outcomes (6)

  • Sleep Apnea Quality of Life Index (SAQLI)

    1 month

  • Quality of Well Being Scale (QWB-SA)

    1 month

  • Self-Efficacy

    1 month

  • +3 more other outcomes

Study Arms (2)

Usual Care

PLACEBO COMPARATOR

Usual sleep apnea and cpap care

Behavioral: Usual care

Self-Management

EXPERIMENTAL

sleep apnea self-management program - 4 sessions, group-based

Behavioral: Sleep Apnea Self-Management Program

Interventions

Sleep apnea self-management program - 4 sessions, group-based.

Self-Management
Usual careBEHAVIORAL

Usual sleep apnea and cpap care

Usual Care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Clinical diagnosis of obstructive sleep apnea
  • No previous use of CPAP
  • Must be a Veteran with residence within San Diego County

You may not qualify if:

  • Home oxygen therapy
  • Fatal comorbidities (i.e., life expectancy less than 6 mos)
  • Contraindications for CPAP use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA San Diego Healthcare System

San Diego, California, 92161, United States

Location

Related Publications (4)

  • Stepnowsky CJ, Palau JJ, Gifford AL, Ancoli-Israel S. A self-management approach to improving continuous positive airway pressure adherence and outcomes. Behav Sleep Med. 2007;5(2):131-46. doi: 10.1080/15402000701190622.

  • Stepnowsky CJ, Palau JJ, Marler MR, Gifford AL. Pilot randomized trial of the effect of wireless telemonitoring on compliance and treatment efficacy in obstructive sleep apnea. J Med Internet Res. 2007 May 17;9(2):e14. doi: 10.2196/jmir.9.2.e14.

  • Stepnowsky CJ, Ancoli-Israel S. Sleep and Its Disorders in Seniors. Sleep Med Clin. 2008;3(2):281-293. doi: 10.1016/j.jsmc.2008.01.011. No abstract available.

  • Deering S, Liu L, Zamora T, Hamilton J, Stepnowsky C. CPAP Adherence is Associated With Attentional Improvements in a Group of Primarily Male Patients With Moderate to Severe OSA. J Clin Sleep Med. 2017 Dec 15;13(12):1423-1428. doi: 10.5664/jcsm.6838.

MeSH Terms

Conditions

Sleep Apnea SyndromesPatient Compliance

Condition Hierarchy (Ancestors)

ApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesPatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Results Point of Contact

Title
Carl J. Stepnowsky,PhD
Organization
VA San Diego Healthcare System

Study Officials

  • Carl J Stepnowsky, PhD

    San Diego Veterans Healthcare System

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 30, 2006

First Posted

April 3, 2006

Study Start

April 1, 2006

Primary Completion

May 1, 2009

Study Completion

December 1, 2009

Last Updated

April 20, 2017

Results First Posted

March 22, 2017

Record last verified: 2017-03

Data Sharing

IPD Sharing
Will not share

Locations