NCT00309868

CompletedPhase 1/2

Study of Nesiritide in Diastolic Heart Failure.

Massachusetts General Hospital Source

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Other study identifiers

Sponsor study identifier

2002-p-001736

Study Type

interventional

Estimated enrollment

20

Locations

0 countries

Sites

N/A

Timeline

Study Start

December 2002

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

December 2003

Actual (reported)

Study Completion

December 2003

Actual (reported)

Brief Summary

We hypothesize that nesiritide will have favorable effect in decreasing heart filling pressures and echocardiogram studies.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Estimated enrollment: 20 participants
Study completion date: December 2003
Actual (reported)
Listed locations: 0 countries · 0 sites

Trial Relationships

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Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
December 2002
Date type not reported
This date has not been verified as actual or estimated.
Primary Completion
December 2003
Actual (reported)
Study Completion
December 2003
Actual (reported)
First Submitted
March 30, 2006
Actual (reported)
First Posted
April 3, 2006
Actual (reported)

Last Updated: March 26, 2014
Status Verified: March 2014
Last Update Submitted: March 24, 2014

Conditions

Diastolic Heart Failure

Keywords

heart catheterizationechocardiogramnesiritide

Interventions

neseritideDrug

Also known as: BNP

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Elevated heart filling pressure. Ejection fraction \>45%. Blood pressure \>90. Physician feels that the patient needs intravenous medication for heart failure.

You may not qualify if:

Sponsors & Collaborators

Scios, Inc.
Industrycollaborator
Massachusetts General Hospital
Otherlead

MeSH Terms

Conditions

Heart Failure, Diastolic

Condition Hierarchy (Ancestors)

Heart FailureHeart DiseasesCardiovascular Diseases

Study Officials

Marc J S, MD
Massachusetts General Hospital
PRINCIPAL INVESTIGATOR

Study Design

Study Type: interventional
Phase: phase 1 2
Allocation: NON RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Medical Director , Heart Failure and Cardiac Transplantation

Study Record Dates

First Submitted

March 30, 2006

First Posted

April 3, 2006

Study Start

December 2002

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

December 2003

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NCT00628082

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Unknown

NCT00303498

A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure

Phase 2Completed

Patients receiving intravenous medication. Patients with significant heart disease or who are unstable. Patients with kidney failure or severe heart valve disease.

Contact the study team to confirm eligibility.

Actual (reported)

Study Completion

December 2003

Actual (reported)

Last Updated

March 26, 2014

Record last verified: 2014-03

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT00309868
Data provider: ClinicalTrials.gov
Source updated: 2014-03-26
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:23:11 UTC

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

Source record