Tranexamic Acid and Head and Neck Surgery Patients
If Tranexamic Acid Could Reduce the Duration of Drainage Tube Placement ? -A Prospective Randomized Study in Head and Neck Surgery Patients
2 other identifiers
interventional
80
1 country
1
Brief Summary
Tranexamic acid belongs to fibrinolytic inhibitors. Several prospective randomized clinical trials have proved its effectiveness in reducing intra-operative and post-operative bleeding in orthopedic and cardiovascular surgeries. However, there is little study about tranexamic acid in reducing post-operative bleeding in head and neck surgery. So the aim of this study is to investigate if tranexamic acid could reduce post-operative bleeding via prospective double-blinded randomized clinic trial.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_3
Started Mar 2006
Shorter than P25 for phase_3
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2006
CompletedFirst Submitted
Initial submission to the registry
March 29, 2006
CompletedFirst Posted
Study publicly available on registry
March 30, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2007
CompletedMarch 30, 2006
March 1, 2006
March 29, 2006
March 29, 2006
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Drainage amount
Drainage stay duration
Laboratoy data
Interventions
Eligibility Criteria
You may qualify if:
- head and neck neoplasm scheduled for operation
You may not qualify if:
- allergy to tranexamic acid
- history of coagulation disorders
- under anti-coagulation therapy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Taichung Veterans General Hospital
Taichung, 40705, Taiwan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Shih-An Liu, MD, MHA
Taichung Veterans General Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
March 29, 2006
First Posted
March 30, 2006
Study Start
March 1, 2006
Study Completion
March 1, 2007
Last Updated
March 30, 2006
Record last verified: 2006-03