Hormone Release and Stomach Disturbances in People With Binge Eating Disorder

NCT00307190 | Completed

• 3 other identifiers: #4735/#5797RR01MH042206-04DATR A2-AID
• Study Type: observational
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

This study will determine whether the disturbances in cholecystokinin release and gastric emptying that occur in people with binge eating disorder are similar to those that occur in people with bulimia nervosa.

Conditions

Binge Eating Disorder; Obesity; Eating Disorders

Keywords

BED

Study Arms (2)

Binge Eating Disorder

Women with Binge Eating Disorder

Controls

Weight, age, and gender-matched control subjects

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Healthy, obese women between ages 18 and 60 with and without Binge Eating Disorder

You may qualify if:

• For all participants:
• Obese (body mass index (BMI) greater than 35 kg/m2)
• For participants with BED:
• Meets DSM-IV criteria for BED
• BED duration of at least 1 year
• For healthy participants:
• Weight close to that of participants with BED

You may not qualify if:

• Current or past diagnosis of BN, or any binge eating or self-induced vomiting
• Significant medical illness
• Current or lifetime history of schizophrenia, bipolar disorder, or other psychotic disorder as defined by DSM-IV-TR
• Current DSM-IV-TR diagnosis of organic mental disorder, factitious disorder, or malingering
• History of a personality disorder (e.g., schizotypal, borderline, or antisocial) that might interfere with assessment or compliance with the study procedures
• At risk for suicide
• Currently taking psychotropic medication or medication that is known to affect appetite or gastric functioning
• History of drug or alcohol abuse within the 3 months prior to study entry
• Pregnant, planning to become pregnant, or lactating
• Anemia

Sponsors & Collaborators

• New York State Psychiatric Institute: lead
• National Institute of Mental Health (NIMH): collaborator

Study Sites (1)

Eating Disorders Clinic, New York State Psychiatric Institute

New York, New York, 10032, United States

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood serum

MeSH Terms

Conditions

Binge-Eating Disorder; Obesity; Feeding and Eating Disorders

Condition Hierarchy (Ancestors)

Mental Disorders; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Signs and Symptoms, Digestive

Study Officials

• B. T. Walsh, MD

  New York State Psychiatric Institute at Columbia University Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 23, 2006
• First Posted: March 27, 2006
• Study Start: October 1, 2004
• Primary Completion: October 1, 2009
• Study Completion: October 1, 2009
• Last Updated: May 28, 2012

Record last verified: 2012-05

Locations

US (1)