Evaluating the Effectiveness of Brief Interpersonal Psychotherapy for Pregnant Women With Depression
Culturally Relevant Brief Interpersonal Psychotherapy (IPT-B) for Perinatal Depression
3 other identifiers
interventional
60
1 country
1
Brief Summary
This study will compare the effectiveness of brief interpersonal psychotherapy versus standard treatment for pregnant women with depression.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable depression
Started Mar 2004
Longer than P75 for not_applicable depression
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2004
CompletedFirst Submitted
Initial submission to the registry
February 15, 2006
CompletedFirst Posted
Study publicly available on registry
February 16, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2007
CompletedSeptember 10, 2012
September 1, 2012
3.8 years
February 15, 2006
September 6, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Depressive symptoms
Measured throughout treatment and at Months 2 and 6 postpartum
Treatment attendance
Measured at Week 12
Study Arms (2)
A
EXPERIMENTALB
ACTIVE COMPARATORInterventions
IPT-B sessions include evaluation of participants' level of depression, identification of any difficulties or problems that participants may be experiencing, and review of how to manage these problems using skills learned during treatment.
F-TAU includes providing verbal and written information regarding depressive symptoms and a referral for treatment at a behavioral health clinic.
Eligibility Criteria
You may qualify if:
- Between 8 and 32 weeks of gestation at time of study entry
- A score above 12 on the Edinburgh Postnatal Depression Scale
- Speaks English
- Resides in the Pittsburgh, PA, area
- Access to a household telephone
You may not qualify if:
- Currently receiving treatment for depression (i.e., medication or psychotherapy)
- History of a prior manic episode
- Alcohol or drug abuse or dependence within 6 months of study entry
- Psychotic disorder or organic mental disorder
- Suicidal, homicidal, or requires hospitalization
- Severe sexual and/or physical aggression in relationship with partner or husband
- Significant medical illness such as epilepsy, autoimmune disorder, liver dysfunction, or unstable endocrine disease
- Severe cognitive deficits that would prevent treatment with psychotherapy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Magee Womens Hospital
Pittsburgh, Pennsylvania, 15213, United States
Related Publications (1)
Jones KA, Freijah I, Brennan SE, McKenzie JE, Bright TM, Fiolet R, Kamitsis I, Reid C, Davis E, Andrews S, Muzik M, Segal L, Herrman H, Chamberlain C. Interventions from pregnancy to two years after birth for parents experiencing complex post-traumatic stress disorder and/or with childhood experience of maltreatment. Cochrane Database Syst Rev. 2023 May 4;5(5):CD014874. doi: 10.1002/14651858.CD014874.pub2.
PMID: 37146219DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Nancy K. Grote, PhD
University of Pittsburgh, School of Social Work
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
February 15, 2006
First Posted
February 16, 2006
Study Start
March 1, 2004
Primary Completion
December 1, 2007
Study Completion
December 1, 2007
Last Updated
September 10, 2012
Record last verified: 2012-09