NCT00287612

Brief Summary

This study compares complete dissection of the tissue around the lower esophagus to no dissection of these tissues during laparoscopic fundoplication in children.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
177

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2006

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2006

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

February 6, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 7, 2006

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2009

Completed
Last Updated

September 22, 2009

Status Verified

March 1, 2009

Enrollment Period

3.5 years

First QC Date

February 6, 2006

Last Update Submit

September 21, 2009

Conditions

Keywords

GERDHiatal HerniaRecurrence

Outcome Measures

Primary Outcomes (1)

  • Hiatal hernia

    1 year

Secondary Outcomes (2)

  • control of symptoms

    1 year

  • retching

    1 year

Study Arms (2)

1

ACTIVE COMPARATOR

Arms:Lap. Fundo. with Mobilization of the Esophageal Junction

Procedure: Lap. Fundo. with Mobilization of the Esophageal Junction

2

EXPERIMENTAL
Procedure: Lap. Fundo. without Mobilization of the Esophageal Junction

Interventions

Complete mobilization of the esophageal junction

1

phrenoesophageal membrane left intact

2

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Under 18 years of age
  • Gastroesophageal Reflux Disease

You may not qualify if:

  • Hiatal hernia demonstrated on preoperative contrast study, computed tomography or endoscopy
  • Prior esophageal operation (e.g. esophageal atresia repair, esophageal myotomy)
  • Prior operation for congenital diaphragmatic hernia
  • Patient or family circumstance that will create difficulty attaining one-year follow-up (e.g. referral from distance or anticipated relocation of family)
  • Patients not considered laparoscopic candidates by the staff surgeon or anesthesiologist (e.g. carbon dioxide retaining lung disease, congenital heart disease, or complex previous abdominal operations)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Children's Hospital of Alabama

Birmingham, Alabama, 35233, United States

Location

Children's Mercy Hospital

Kansas City, Missouri, 64108, United States

Location

Related Publications (1)

  • van der Does de Willebois EML; SPICY study group. Mesenteric SParIng versus extensive mesentereCtomY in primary ileocolic resection for ileocaecal Crohn's disease (SPICY): study protocol for randomized controlled trial. BJS Open. 2022 Jan 6;6(1):zrab136. doi: 10.1093/bjsopen/zrab136.

MeSH Terms

Conditions

Gastroesophageal RefluxHernia, HiatalRecurrence

Condition Hierarchy (Ancestors)

Esophageal Motility DisordersDeglutition DisordersEsophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesHernia, DiaphragmaticInternal HerniaHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsDisease AttributesPathologic Processes

Study Officials

  • Shawn D St. Peter, MD

    Children's Mercy Hospital Kansas City

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 6, 2006

First Posted

February 7, 2006

Study Start

February 1, 2006

Primary Completion

August 1, 2009

Study Completion

August 1, 2009

Last Updated

September 22, 2009

Record last verified: 2009-03

Locations