NCT00279643

CompletedPhase 1/2

The Effect of Laser Hair Removal on Permanent Hair Reduction

University of Michigan Source

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Other study identifiers

Sponsor study identifier

Derm 543

Study Type

interventional

Reported enrollment (type unavailable)

60

Locations

1 country

Sites

1

Timeline

Study Start

January 2005

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

Not reported

Date not reported

Study Completion

June 2006

Actual (reported)

Brief Summary

The purpose of this study is to learn more about how hair removal with lasers achieves, what appears to be, permanent hair reduction. Laser hair removal has become one of the most popular and commonly performed procedures in cosmetic dermatology. However, relatively little is known about how the permanent reduction in the treated areas occurs. Recently, it has been discovered that certain cells in the hair follicle must be destroyed in order to achieve permanent hair reduction. A marker of these types of cells known as keratin 15 has been identified. By measuring the amount of keratin 15 before and after laser therapy, we hope to gain a better understanding of how lasers cause hair reduction on a biochemical level.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Reported enrollment (type unavailable): 60 participants
Study completion date: June 2006
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

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Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
January 2005
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
January 17, 2006
Actual (reported)
First Posted
January 19, 2006
Actual (reported)
Study Completion
June 2006
Actual (reported)

Last Updated: April 30, 2015
Status Verified: April 2015
Last Update Submitted: April 29, 2015

Conditions

Laser Hair Removal in Healthy Subjects

Keywords

Laserimmunohistochemical stainingLaser Hair Removalfollicular stem cellskeratin 15

Outcome Measures

Primary Outcomes (1)

measurement of the effects of laser hair removal on the immunohistochemical staining properties of human hair follicles, including the putative stem cells of the bulge region.

Secondary Outcomes (1)

Hair Removal

Interventions

Laser Hair RemovalProcedure

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Age 18 years or older of either gender.
At least moderately dense axillary (armpit) hair that is dark (not blonde or white) in color.

Sponsors & Collaborators

University of Michigan
Otherlead

Study Sites (1)

University of Michigan Department of Dermatology

Ann Arbor, Michigan, 48109, United States

Study Officials

John J Voorhees, MD
University of Michigan
STUDY CHAIR

Study Design

Study Type: interventional
Phase: phase 1 2
Allocation: RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Professor of Dermatology, Medical School

Study Record Dates

First Submitted

January 17, 2006

First Posted

January 19, 2006

Study Start

January 2005

Date type not reported

This date has not been verified as actual or estimated.

Study Completion

June 2006

Subjects must understand and sign the informed consent documents prior to participation.

Subjects must be in generally good health.

Subjects must be willing and able to comply with the requirements of the protocol

You must live within a reasonable driving distance of Ann Arbor, Michigan, and/or be able to attend all of the scheduled appointments during the study.

You may not qualify if:

Oral retinoid use within one year of study entry.
History of prior laser therapy or electrolysis of the axillae.
Subjects who do not desire permanent reduction in axillary hair.
Non-compliant subjects.
Pregnant or nursing subjects.
Subjects with a significant medical history or concurrent illness/condition that the investigator(s) feel is not safe for study participation.
Active infection of the site to be treated or a history of herpes simplex or zoster infection at the site to be treated.
History of keloid scar formation.
Known history of allergy or sensitivity to lidocaine.
History of waxing, plucking, or bleaching of the hair for 6 weeks prior to the treatment.

Contact the study team to confirm eligibility.

Actual (reported)

Last Updated

April 30, 2015

Record last verified: 2015-04

Source record

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Source: ClinicalTrials.gov.

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Registry identifier: NCT00279643
Data provider: ClinicalTrials.gov
Source updated: 2015-04-30
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:39:25 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Officials

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations