Prevalence of HIV and Other Sexually Transmitted Infections Among Female Sex Workers and Miners in Honghe Prefecture, Yunnan Province, China

NCT00278499 | Completed

• 2 other identifiers: CIPRA CH 005CIPRA Project 1
• Study Type: observational
• Target: 3,800
• Locations: 1 country
• Sites: 2

Brief Summary

The purpose of this study is to collect data on the HIV strains currently circulating among female sex workers (FSWs) and their clients. In addition, this study will identify potential participants for future studies.

Conditions

HIV Infections; Sexually Transmitted Diseases

Outcome Measures

Primary Outcomes (2)

• Incidence of HIV-1 infection in FSWs and mine workers

  Throughout study

• Risk factors for HIV-1 infection including, but not limited to injection drug use, STIs, and unprotected sex among FSWs and mine workers separately

  Throughout study

Secondary Outcomes (4)

• Prevalence of HIV-1 infection and selected STIs

  Throughout study

• HIV/STI related knowledge, attitudes, and risk behaviors in FSWs and mine workers separately

  Throughout study

• HIV-1 viral subtypes in FSWs and mine workers separately

  Throughout study

• FSW migration patterns in a sub-cohort of FSWs

  Throughout study

Study Arms (2)

1

Female sex workers

Behavioral: Cross-sectional surveys

2

Female sex workers' clients (miners)

Behavioral: Questionnaire/counseling

Interventions

Cross-sectional surveys BEHAVIORAL

Cross-sectional surveys will occur at study entry, Month 6, and Month 12. Every fourth participant enrolled in the FSW cross-sectional survey, all FSWs found to be HIV infected, and all FSWs who are intravenous drug users will participate in a substudy lasting 12 months.

1

Questionnaire/counseling BEHAVIORAL

An initial questionnaire and counseling will occur once in addition to post-test counseling.

2

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Female sex workers and their clients in Hinghe Prefecture, Yunnan Province, China

You may qualify if:

• Self-reported to have sold sex for money within the 3 months prior to study entry
• Works at one of the study sites
• Participated in the baseline cross-sectional survey in Kaiyuan City, Honghe Prefecture, Yunnan Province, China
• Willing to provide updated contact information (and a cell phone number, if available)
• Willing to be contacted by study staff once a month for 12 consecutive months
• Male
• Works at one of the selected mine sites
• Parent or guardian willing to provide informed consent, if applicable

Sponsors & Collaborators

• National Institute of Allergy and Infectious Diseases (NIAID): lead

Study Sites (2)

Gejiu CDC, Honghe Prefecture, Yunnan Province

Kunming, Yunnan, China

Location

Kaiyuan CDC, Honghe

Kunming, Yunnan, China

Location

Related Publications (5)

• Anderson AF, Qingsi Z, Hua X, Jianfeng B. China's floating population and the potential for HIV transmission: a social-behavioural perspective. AIDS Care. 2003 Apr;15(2):177-85. doi: 10.1080/0954012031000068326.

  PMID: 12856339 BACKGROUND

• Chen XS, Yin YP, Liang GJ, Gong XD, Li HS, Poumerol G, Thuy N, Shi MQ, Yu YH. Sexually transmitted infections among female sex workers in Yunnan, China. AIDS Patient Care STDS. 2005 Dec;19(12):853-60. doi: 10.1089/apc.2005.19.853.

  PMID: 16375618 BACKGROUND

• Ding Y, Detels R, Zhao Z, Zhu Y, Zhu G, Zhang B, Shen T, Xue X. HIV infection and sexually transmitted diseases in female commercial sex workers in China. J Acquir Immune Defic Syndr. 2005 Mar 1;38(3):314-9.

  PMID: 15735451 BACKGROUND

• Tucker JD, Henderson GE, Wang TF, Huang YY, Parish W, Pan SM, Chen XS, Cohen MS. Surplus men, sex work, and the spread of HIV in China. AIDS. 2005 Mar 24;19(6):539-47. doi: 10.1097/01.aids.0000163929.84154.87.

  PMID: 15802971 BACKGROUND

• Zhao R, Gao H, Shi X, Tucker JD, Yang Z, Min X, Qian H, Duan Q, Wang N. Sexually transmitted disease/HIV and heterosexual risk among miners in townships of Yunnan Province, China. AIDS Patient Care STDS. 2005 Dec;19(12):848-52. doi: 10.1089/apc.2005.19.848.

  PMID: 16375617 BACKGROUND

MeSH Terms

Conditions

HIV Infections; Sexually Transmitted Diseases

Interventions

Cross-Sectional Studies; Surveys and Questionnaires; Counseling

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Epidemiologic Studies; Epidemiologic Study Characteristics; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health; Data Collection; Mental Health Services; Behavioral Disciplines and Activities; Community Health Services; Health Services; Health Care Facilities Workforce and Services

Study Officials

• Ning Wang, MD, PhD

  Chinese Center for Disease Control and Prevention, National Center for AIDS/STD Prevention and Control

  PRINCIPAL INVESTIGATOR

• Zhongmin Yang, MD

  Chinese Center for Disease Control and Prevention, National Center for AIDS/STD Prevention and Control

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: NIH

Study Record Dates

• First Submitted: January 16, 2006
• First Posted: January 18, 2006
• Study Start: March 1, 2006
• Primary Completion: January 1, 2011
• Study Completion: January 1, 2011
• Last Updated: January 13, 2011

Record last verified: 2011-01

Locations

CN (2)