NCT00275717|Completed
A Study That Will Look at the Impact of Immunosuppression on Antibody Production in Kidney Transplant Recipients.
The Effects of Thymoglobulin on Antibody Screening Cells.
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The Effects of Thymoglobulin on Antibody Screening Cells.
Sponsor study identifier
observational
60
1 country
1
Study Start
March 2005
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2010
Actual (reported)Study Completion
December 2010
Actual (reported)This study is being done to collect blood and bone marrow samples for biologic studies of antibody producing cells. Donor specific antibodies can cause damage to the kidneys after they are transplanted. The study will look at the impact of immunosuppression on antibody production by antibody producing cells.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2010
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 2005
Date type not reportedThis date has not been verified as actual or estimated.
January 10, 2006
Actual (reported)January 12, 2006
Actual (reported)December 2010
Actual (reported)December 2010
Actual (reported)Three groups will be studied: 1. Non-sensitized renal allograft candidates prior to any therapy; 2. High DSA recipients--Recipients with a positive T or B cell cytotoxicity crossmatch or a B cell flow cytometric crossmatch assay with a channel shift \>350 at baseline against their living donor at baseline and 3. Low DSA recipients-recipients with a negative T and B cell cytotoxicity assay, but a positive T or B cell flow cytometric crossmatch with a B cell channel shift \<350.
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
Mayo Clinic
Rochester, Minnesota, 55905, United States
Mark D. Stegall, M.D.
Mayo Clinic
60 participants (actual enrollment reported by the registry).
First Submitted
January 10, 2006
First Posted
January 12, 2006
Study Start
March 2005
Date type not reportedThis date has not been verified as actual or estimated.
Immunophenotyping of Peripheral T Cells After T Cell Depletion With Alemtuzumab
Primary Completion
December 2010
Actual (reported)Study Completion
December 2010
Actual (reported)Last Updated
December 22, 2010
Record last verified: 2010-12
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Source: ClinicalTrials.gov.
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