Genzyme, a Sanofi Company
523
12
21
374
Key Highlights
Risk & Performance
Pipeline Risk Assessment
Pipeline Risk Assessment
Based on historical performance
High Risk
Score: 65/100
18.9%
99 terminated/withdrawn out of 523 trials
79.1%
-7.4% vs industry average
25%
132 trials in Phase 3/4
49%
182 of 374 completed trials have results
Key Signals
Enrollment Performance
Analytics
Activity Timeline
Global Presence
Clinical Trials (523)
Pompe Disease Registry Protocol
Role: lead
Fabry Disease Registry & Pregnancy Sub-registry
Role: lead
Pompe Pregnancy Sub-Registry
Role: lead
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
Role: lead
Determination of CRIM Status and Longitudinal Follow-up of Individuals With Pompe Disease
Role: collaborator
China Post-approval Commitment (PAC) Study of Avalglucosidase Alfa in Participants With IOPD
Role: lead
Isatuximab, Carfilzomib, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma
Role: collaborator
Anti-PD-1 Re-challenge After Immune Priming by Ipilimumab and Immune Boosting by Radiotherapy in Advanced NSCLC
Role: collaborator
Mucopolysaccharidosis I (MPS I) Registry
Role: lead
A Study to Assess Safety and Efficacy of Avalglucosidase Alfa Administered Every Other Week in Pediatric Patients With Infantile-onset Pompe Disease Previously Treated With Alglucosidase Alfa
Role: lead
A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2
Role: lead
A Phase I/II Study to Assess the Safety and Efficacy of Vaccinations With Allogeneic Dendritic Cells: Autologous Tumor-Derived Cells Subjected to Electrofusions in Patients With AJCC Stage IV Renal Cell Carcinoma
Role: collaborator
The Use of Dendritic Cell/Tumor Hybridomas as a Novel Tumor Vaccine in Patients With Advance Melanoma
Role: collaborator
The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients
Role: collaborator
Glucose Consumption in MS Using [F-18]FDG-PET
Role: collaborator
Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX
Role: lead
Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma
Role: collaborator
A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMT
Role: lead
Efficacy of Dupilumab on Facilitated Food Introduction in Eosinophilic Esophagitis
Role: collaborator
Avalglucosidase Alfa French Post-trial Access for Participants With Pompe Disease (PTA Avalglucosidase)
Role: lead