NCT00271128

Brief Summary

The proposed study intends to evaluate the impact of the NT-proBNP assay on the diagnosis of heart failure in patients with dyspnea of unknown etiology presenting to the emergency room and admitted to the medical wards.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2005

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2005

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

December 29, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 30, 2005

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2007

Completed
Last Updated

March 20, 2008

Status Verified

December 1, 2005

First QC Date

December 29, 2005

Last Update Submit

March 19, 2008

Conditions

Shortness of BreathAcute Exacerbation

Keywords

NT-proBNPHeart failureDyspnea

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Acute shortness of breath of unknown etiology as presentation to the emergency room
  • Possible acute exacerbation of known heart failure

You may not qualify if:

  • None -

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hillel Yaffe Medical Center

Hadera, Israel

Location

Related Publications (1)

  • Meisel SR, Januzzi JL, Medvedovski M, Sharist M, Shochat M, Ashkar J, Peschansky P, Haim SB, Blondheim DS, Glikson M, Shotan A. Pre-admission NT-proBNP improves diagnostic yield and risk stratification - the NT-proBNP for EValuation of dyspnoeic patients in the Emergency Room and hospital (BNP4EVER) study. Eur Heart J Acute Cardiovasc Care. 2012 Jun;1(2):99-108. doi: 10.1177/2048872612447049.

    PMID: 24062895DERIVED

MeSH Terms

Conditions

DyspneaHeart Failure

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract DiseasesSigns and Symptoms, RespiratorySigns and SymptomsPathological Conditions, Signs and SymptomsHeart DiseasesCardiovascular Diseases

Study Officials

  • Simcha R Meisel, MD MSc

    Hillel Yaffe Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

December 29, 2005

First Posted

December 30, 2005

Study Start

October 1, 2005

Study Completion

September 1, 2007

Last Updated

March 20, 2008

Record last verified: 2005-12

Locations

IL(1)