NCT00269347

Brief Summary

The broad, long term objective of this interdisciplinary research is to identify effective therapies for low back pain sufferers and to increase our understanding of this important condition. The primary aim is to examine the relative efficacy of chiropractic spinal manipulation, rehabilitative exercise, and self-care education in terms of patient-rated outcomes in the short and long term for non-acute low back pain.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for phase_2 low-back-pain

Timeline
Completed

Started Jan 2001

Longer than P75 for phase_2 low-back-pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2001

Completed
4.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2005

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

December 21, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 23, 2005

Completed
Last Updated

December 23, 2005

Status Verified

December 1, 2005

First QC Date

December 21, 2005

Last Update Submit

December 22, 2005

Conditions

Keywords

ChiropracticManual TherapyExerciseRandomizedClinical TrialBack Pain

Outcome Measures

Primary Outcomes (1)

  • Pain (Visual Analog Scale) at baseline, weeks 4,12,26,52

Secondary Outcomes (13)

  • Disability (Modified Roland Scale) at baseline, weeks 4,12,26,52

  • General Health (SF-36) at baseline, weeks 4,12,26,52

  • Improvement (7 point scale) at baseline, weeks 4,12,26,52

  • Disability (NHIS) at baseline, weeks 4,12,26,52

  • Bothersomeness (7 point scale) at baseline, weeks 4,12,26,52

  • +8 more secondary outcomes

Interventions

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may not qualify if:

  • previous lumbar spine surgery; back pain referred from local joint lesions of the lower extremities or from visceral diseases; progressive neurological deficits due to nerve root or spinal cord compression; aortic and peripheral vascular disease; existing cardiac disease requiring medical treatment; blood clotting disorders; diffuse idiopathic hyperostosis; infectious and noninfectious inflammatory or destructive tissue changes of the lumbar spine; presence of significant infectious disease, or other severe debilitating health problems; substance abuse; ongoing treatment for back pain by other health care providers; pregnant or nursing women; pain score of less than 30 percentage points; pending our current litigation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Northwestern Health Sciences University

Bloomington, Minnesota, 55431, United States

Location

Related Publications (2)

  • Haanstra TM, Hanson L, Evans R, van Nes FA, De Vet HC, Cuijpers P, Ostelo RW. How do low back pain patients conceptualize their expectations regarding treatment? Content analysis of interviews. Eur Spine J. 2013 Sep;22(9):1986-95. doi: 10.1007/s00586-013-2803-8. Epub 2013 May 10.

  • Bronfort G, Maiers MJ, Evans RL, Schulz CA, Bracha Y, Svendsen KH, Grimm RH Jr, Owens EF Jr, Garvey TA, Transfeldt EE. Supervised exercise, spinal manipulation, and home exercise for chronic low back pain: a randomized clinical trial. Spine J. 2011 Jul;11(7):585-98. doi: 10.1016/j.spinee.2011.01.036. Epub 2011 May 31.

Related Links

MeSH Terms

Conditions

Low Back PainMotor ActivityBack Pain

Interventions

Manipulation, ChiropracticExerciseSelf Care

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsBehavior

Intervention Hierarchy (Ancestors)

Musculoskeletal ManipulationsComplementary TherapiesTherapeuticsMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaRehabilitationHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Gert Bronfort, DC, PhD

    Northwestern Health Sciences University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 21, 2005

First Posted

December 23, 2005

Study Start

January 1, 2001

Study Completion

April 1, 2005

Last Updated

December 23, 2005

Record last verified: 2005-12

Locations