NCT00269256|Completed
Loading search results
Sponsor study identifier
Secondary identifiers
NIH
observational
959
1 country
1
Study Start
September 2005
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
March 2010
Actual (reported)Study Completion
March 2010
Actual (reported)The purpose of this study is to evaluate the multiple mechanisms through which stress, physical environment, and genetic predisposition contribute to asthma in urban children.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 2010
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 2005
Date type not reportedThis date has not been verified as actual or estimated.
December 21, 2005
Actual (reported)December 23, 2005
Actual (reported)March 2010
Actual (reported)March 2010
Actual (reported)Pregnant women and their children followed over first 5 years.
Contact the study team to confirm eligibility.
Brigham & Women's Hospital
Boston, Massachusetts, 02115, United States
Wright RJ, Fisher K, Chiu YH, Wright RO, Fein R, Cohen S, Coull BA. Disrupted prenatal maternal cortisol, maternal obesity, and childhood wheeze. Insights into prenatal programming. Am J Respir Crit Care Med. 2013 Jun 1;187(11):1186-93. doi: 10.1164/rccm.201208-1530OC.
Chiu YH, Coull BA, Cohen S, Wooley A, Wright RJ. Prenatal and postnatal maternal stress and wheeze in urban children: effect of maternal sensitization. Am J Respir Crit Care Med. 2012 Jul 15;186(2):147-54. doi: 10.1164/rccm.201201-0162OC. Epub 2012 May 10.
Maternal DNA Child DNA
Rosalind Wright
Brigham and Women's Hospital
959 participants (actual enrollment reported by the registry).
First Submitted
December 21, 2005
First Posted
December 23, 2005
Study Start
September 2005
Date type not reportedThis date has not been verified as actual or estimated.
Optimal Approach for Analysis of Case-Control Genetic Association Studies
Peters JL, Cohen S, Staudenmayer J, Hosen J, Platts-Mills TA, Wright RJ. Prenatal negative life events increases cord blood IgE: interactions with dust mite allergen and maternal atopy. Allergy. 2012 Apr;67(4):545-51. doi: 10.1111/j.1398-9995.2012.02791.x. Epub 2012 Feb 6.
Tse AC, Rich-Edwards JW, Koenen K, Wright RJ. Cumulative stress and maternal prenatal corticotropin-releasing hormone in an urban U.S. cohort. Psychoneuroendocrinology. 2012 Jul;37(7):970-9. doi: 10.1016/j.psyneuen.2011.11.004. Epub 2011 Dec 9.
Sternthal MJ, Coull BA, Chiu YH, Cohen S, Wright RJ. Associations among maternal childhood socioeconomic status, cord blood IgE levels, and repeated wheeze in urban children. J Allergy Clin Immunol. 2011 Aug;128(2):337-45.e1. doi: 10.1016/j.jaci.2011.05.008. Epub 2011 Jun 25.
Chiu YH, Coull BA, Sternthal MJ, Kloog I, Schwartz J, Cohen S, Wright RJ. Effects of prenatal community violence and ambient air pollution on childhood wheeze in an urban population. J Allergy Clin Immunol. 2014 Mar;133(3):713-22.e4. doi: 10.1016/j.jaci.2013.09.023. Epub 2013 Nov 4.
Primary Completion
March 2010
Actual (reported)Study Completion
March 2010
Actual (reported)Last Updated
February 3, 2016
Record last verified: 2016-02
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: